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Pharmaceutical Chemistry Journal

, Volume 44, Issue 10, pp 525–527 | Cite as

Synthesis and antioxidant activity of new 1,2,4-triazole derivatives

  • T. V. Kochikyan
  • M. A. Samvelyan
  • E. V. Arutyunyan
  • V. S. Arutyunyan
  • A. A. Avetisyan
  • M. G. Malakyan
  • L. A. Vardevanyan
  • S. A. Badzhinyan
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A series of new derivatives of 1,2,4-triazoles have been synthesized and their antioxidant properties have been studied. It was established that the obtained compounds exhibit a stabilizing effect on cell membranes and demonstrate antioxidant activity with respect to erythrocytes under oxidative stress conditions.

Key words

1,2,4-triazole derivatives erythrocytes membrane stabilizing effect antioxidant activity 

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Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  • T. V. Kochikyan
    • 1
  • M. A. Samvelyan
    • 1
  • E. V. Arutyunyan
    • 1
  • V. S. Arutyunyan
    • 1
  • A. A. Avetisyan
    • 1
  • M. G. Malakyan
    • 2
  • L. A. Vardevanyan
    • 2
  • S. A. Badzhinyan
    • 2
  1. 1.Yerevan State UniversityYerevanArmenia
  2. 2.Scientific Centre of Radiation Medicine and BurnsYerevanArmenia

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