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Pharmaceutical Chemistry Journal

, Volume 44, Issue 8, pp 446–451 | Cite as

Palladium catalysts in the synthesis of local anesthetics (review)

  • M. V. Klyuev
  • M. G. Abdullaev
  • Z. Sh. Abdullaeva
DRUG SYNTHESIS METHODS AND MANUFACTURING TECHNOLOGY

Catalytic processes involving Pd-containing catalysts for the synthesis of local anesthetics such as anesthesin (benzocaine), novocaine (procaine), lidocaine, mepivacaine, bupivacaine, trimecaine, and pyromecaine (bumecaine) are reviewed.

Key words

local anesthetics synthesis Pd-containing anion-exchangers hydrogenation hydroamination hydroacylation 

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Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  • M. V. Klyuev
    • 1
  • M. G. Abdullaev
    • 2
  • Z. Sh. Abdullaeva
    • 2
  1. 1.Ivanovo State UniversityIvanovoRussia
  2. 2.Derbent Branch of Ivanovo State UniversityDerbentRussia

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