A series of 2-acetyl-5-hydroxy-5-methyl-3-phenyl-1-cyclohexanone and alkyl-4-hydroxy-4-methyl-2-oxo6-phenylcyclohexane-1-carboxylates have been obtained via interaction of benzalacetone with various acetoacetates and acetylacetone in an ethanol solution of potassium hydroxide. The antimicrobial activity of the synthesized compounds has been studied.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 44, No. 5, pp. 13 – 15, May, 2010.
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Gein, V.L., Vagapov, A.V., Nosova, N.V. et al. Synthesis and antimicrobial activity of 2-acetyl-5-hydroxy-5-methyl-3-phenyl-1cyclohexanone and alkyl-4-hydroxy-4-methyl2-oxo-6-phenylcyclohexane-1-carboxylates. Pharm Chem J 44, 245–247 (2010). https://doi.org/10.1007/s11094-010-0440-7
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DOI: https://doi.org/10.1007/s11094-010-0440-7