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Pharmaceutical Chemistry Journal

, Volume 44, Issue 5, pp 245–247 | Cite as

Synthesis and antimicrobial activity of 2-acetyl-5-hydroxy-5-methyl-3-phenyl-1cyclohexanone and alkyl-4-hydroxy-4-methyl2-oxo-6-phenylcyclohexane-1-carboxylates

  • V. L. Gein
  • A. V. Vagapov
  • N. V. Nosova
  • E. V. Voronina
  • M. I. Vakhrin
  • A. P. Kriven’ko
Article

A series of 2-acetyl-5-hydroxy-5-methyl-3-phenyl-1-cyclohexanone and alkyl-4-hydroxy-4-methyl-2-oxo6-phenylcyclohexane-1-carboxylates have been obtained via interaction of benzalacetone with various acetoacetates and acetylacetone in an ethanol solution of potassium hydroxide. The antimicrobial activity of the synthesized compounds has been studied.

Key words

cyclohexanone cyclohexanecarboxylates antimicrobial activity β-cycloketoles alkyl-2oxocyclohexanecarboxylates 

References

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    V. L. Gein, A. A. Zorina, N. V. Gein, and E. V. Voronina, Khim.farm. Zh., 39(4), 21 – 23 (2005).Google Scholar
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Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  • V. L. Gein
    • 1
  • A. V. Vagapov
    • 1
  • N. V. Nosova
    • 1
  • E. V. Voronina
    • 1
  • M. I. Vakhrin
    • 1
  • A. P. Kriven’ko
    • 2
  1. 1.Perm State Pharmaceutical AcademyPermRussia
  2. 2.Saratov State UniversitySaratovRussia

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