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Pharmaceutical Chemistry Journal

, Volume 44, Issue 2, pp 107–109 | Cite as

Planar chromatography in studies of optically active drugs

  • V. P. Pakhomov
  • O. A. Checha
Article
  • 37 Downloads

The use of planar chromatography for the investigation and separation of optically active drugs into individual stereoisomers with subsequent identification of isomers was demonstrated using amino acids and amlodipine besylate as examples.

Key words

Optically active drugs amino acids amlodipine besylate planar chromatography 

References

  1. 1.
    N. I. Tyukavkina and Yu. I. Baukov, Bioorganic Chemistry, [in Russian], Drofa, Moscow (2008), pp. 67 – 115.Google Scholar
  2. 2.
    M. D. Mashkovskii, Drugs [in Russian], Novaya Volna, Moscow (2002), Vol. 2, pp. 124 – 125.Google Scholar
  3. 3.
    V. A. Davankov, A. S. Bochkov, and R. K. Unger, Chromatogr., 13, 677 – 680 (1980).CrossRefGoogle Scholar
  4. 4.
    F. Geis, Basic Thin-Layer Chromatography [in Russian], Moscow (1999), Vol. 2, pp. 110 – 120.Google Scholar
  5. 5.
    V. D. Krasikov, Basic Planar Chromatography [in Russian], Khimizdat, St. Petersburg (2005), pp. 34 – 35.Google Scholar
  6. 6.
    E. G. Sumina, S. N. Shtykov, and N. V. Tyurina, Thin-Layer Chromatography. Theoretical Bases and Practical Applications [in Russian], Saratov (2006), pp. 22 – 41.Google Scholar
  7. 7.
    V. P. Pakhomov and O. A. Checha, Ved. Nauchn. Tsentr. Ékspert. Sredstv Med. Primen., No. 3, 38 – 42 (2006).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  • V. P. Pakhomov
    • 1
  • O. A. Checha
    • 1
  1. 1.Institute of Clinical PharmacologyScientific Center for Expertise in Drug UseMoscowRussia

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