Preparation of a liposomal form of butaminophen by mechanical dispersion
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The physicochemical conditions for incorporation of the antiviral agent butaminophen into multilamellar liposomes generated by mechanical dispersion were determined. Regimes for vortexing of the liposome-forming mixture to obtain a homogeneous liposome suspension were identified. This liposomal formulation has potential for the development of oral (gelatin capsules) and ointment formulations.
Key wordsHerpes infections butaminophen multilamellar liposomes vortexing
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