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Pharmaceutical Chemistry Journal

, Volume 43, Issue 4, pp 219–221 | Cite as

Preparation of a liposomal form of butaminophen by mechanical dispersion

  • I. M. Bushmakina
  • N. I. Drozdova
  • N. S. Golenko
  • M. A. Martynova
Medicinal Plants
  • 42 Downloads

The physicochemical conditions for incorporation of the antiviral agent butaminophen into multilamellar liposomes generated by mechanical dispersion were determined. Regimes for vortexing of the liposome-forming mixture to obtain a homogeneous liposome suspension were identified. This liposomal formulation has potential for the development of oral (gelatin capsules) and ointment formulations.

Key words

Herpes infections butaminophen multilamellar liposomes vortexing 

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References

  1. 1.
    L. N. Dunets, O. I. Shadyro, G. I. Polozov, et al., Proceedings of the VI Russian National Congress “Humans and Medicines” [in Russian], Moscow (1999), p. 405.Google Scholar
  2. 2.
    L. N. Dunets, P. T. Petrov, V. E. Spiridonov, et al., Proceedings of the IX Russian National Congress “Humans and Medicines” [in Russian], Moscow (2002). P. 142.Google Scholar
  3. 3.
    V. G. Pankratov, S. A. Gumbar, O. V. Pankratov, et al., Proceedings of the IX Russian National Congress “Humans and Medicines” [in Russian], Moscow (2002). P. 457.Google Scholar
  4. 4.
    I. A. Bakker-Woudenberg, A. F. Lokerse, M. T. Kate, et al., Eur. J. Clin. Microbiol. Infect. Dis., 12(1), 61 – 67 (1993).CrossRefGoogle Scholar
  5. 5.
    N. Van Rooijen, Adv. Exp. Med. Biol., 355(1), 69 – 74 (1994).PubMedGoogle Scholar
  6. 6.
    I. M. Bushmakina, V. K. Matus, M. A. Martynova, et al., Novosti Mediko-Biologicheskikh Nauk, No. 2, 110 – 114 (2004).Google Scholar
  7. 7.
    V. K. Matus, G. L. Gurevich, S. V. Konev, et al., Vestsi NAN Belarusi Ser. Biyal. Navuk., No. 1, 131 – 141 (2000).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • I. M. Bushmakina
    • 1
  • N. I. Drozdova
    • 1
  • N. S. Golenko
    • 1
  • M. A. Martynova
    • 1
  1. 1.State Scientific Institute “Institute of Biophysics and Cellular EngineeringNational Academy of Sciences, Belarus”MinskBelarus

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