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Evaluation of the purity of vitamin a oil-based preparations by thin-layer chromatography

  • Structure of Chemical Compounds, Methods of Analysis and Process Control
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Pharmaceutical Chemistry Journal Aims and scope

An important stage in pharmaceutical analysis is the estimation of the degree of purity of parent substances and related preparations. There is currently a need to develop simple, economic, and accessible methods for rapid analysis. One such method is thin-layer chromatography (TLC). In the present work, the possibility of using TLC for monitoring the content of impurities in oil-based vitamin A preparations and for their separation and identification is considered.

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Authors and Affiliations

  1. Voronezh State University, Voronezh, Russia

    O. V. Checheta, E. F. Safonova, A. I. Slivkin & G. A. Ogol’

Authors
  1. O. V. Checheta
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  2. E. F. Safonova
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  3. A. I. Slivkin
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  4. G. A. Ogol’
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 12, pp. 47–49, December, 2008.

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Checheta, O.V., Safonova, E.F., Slivkin, A.I. et al. Evaluation of the purity of vitamin a oil-based preparations by thin-layer chromatography. Pharm Chem J 42, 721–723 (2008). https://doi.org/10.1007/s11094-009-0210-6

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  • DOI: https://doi.org/10.1007/s11094-009-0210-6

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