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Spectrophotometric assay of active components in medicinal formulations using the Vierordt method. I. Analysis of analgin-quinine and panadol extra

  • Structure of Chemical Compounds, Methods of Analysis and Process Control
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Pharmaceutical Chemistry Journal Aims and scope

A method for the spectrophotometric assay of Analgin, caffeine, quinine hydrochloride, and paracetamol in two-component medicinal formulations was developed using a new criterion for selecting analytical wavelengths (AWL). Content calculations were performed using several sets of AWL. Model solutions were used to show that use of three sets of AWL decreases estimation errors for components in mixtures with both low and high contents. This method was used to analyze the medicinal formulations Panadol Extra and Analgin-quinine.

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Authors and Affiliations

  1. F. M. Dostoevskii Omsk State University, Omsk, Russia

    I. V. Vlasova, A. V. Shilova & Yu. S. Fokina

Authors
  1. I. V. Vlasova
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  2. A. V. Shilova
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  3. Yu. S. Fokina
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 10, pp. 49–53, October, 2008.

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Vlasova, I.V., Shilova, A.V. & Fokina, Y.S. Spectrophotometric assay of active components in medicinal formulations using the Vierordt method. I. Analysis of analgin-quinine and panadol extra. Pharm Chem J 42, 599–603 (2008). https://doi.org/10.1007/s11094-009-0179-1

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  • DOI: https://doi.org/10.1007/s11094-009-0179-1

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