Pharmaceutical Chemistry Journal

, Volume 42, Issue 10, pp 599–603 | Cite as

Spectrophotometric assay of active components in medicinal formulations using the Vierordt method. I. Analysis of analgin-quinine and panadol extra

  • I. V. Vlasova
  • A. V. Shilova
  • Yu. S. Fokina
Structure of Chemical Compounds, Methods of Analysis and Process Control

A method for the spectrophotometric assay of Analgin, caffeine, quinine hydrochloride, and paracetamol in two-component medicinal formulations was developed using a new criterion for selecting analytical wavelengths (AWL). Content calculations were performed using several sets of AWL. Model solutions were used to show that use of three sets of AWL decreases estimation errors for components in mixtures with both low and high contents. This method was used to analyze the medicinal formulations Panadol Extra and Analgin-quinine.


Caffeine Paracetamol Model Mixture Quinine Spectrophotometric Assay 
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  1. 1.
    I. Ya. Bershtein and Yu. A. Kaminskii, Spectrophotometric Analysis in Organic Chemistry [in Russian], Khimiya, Leningrad (1986), pp. 58–85.Google Scholar
  2. 2.
    M. D. Kats and M. Ya. Rozkin, Zav. Lab., 38(6), 688 (1972).Google Scholar
  3. 3.
    A. F. Vasil'ev, M. B. Pankova, and Yu. Markosh, Zav. Lab., 39(9), 1073 (1973).Google Scholar
  4. 4.
    I. G. Per'kov, A. V. Droza, and G. V. Artsebashev, Zh. Analit. Khimii, 42(1), 68 (1987).Google Scholar
  5. 5.
    I. G. Per'kov, G. V. Artsebashev, A. V. Droza, et al., Zh. Analit. Khim., 42(11), 1951 (1987).Google Scholar
  6. 6.
    A. I. Grizodub, M. G. Levin, and V. P. Georgievskii, Zh. Analit. Khim., 42(9), 1589 (1987).Google Scholar
  7. 7.
    A. I. Grizodub, N. N. Asmolova, V. P. Georgievskii, et al., Zh. Analit. Khim., 44(10), 1824 (1989).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2008

Authors and Affiliations

  • I. V. Vlasova
    • 1
  • A. V. Shilova
    • 1
  • Yu. S. Fokina
    • 1
  1. 1.F. M. Dostoevskii Omsk State UniversityOmskRussia

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