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Pharmaceutical Chemistry Journal

, Volume 42, Issue 3, pp 153–156 | Cite as

Quantitative HPLC determination of phenolic compounds in yarrow

  • R. Benetis
  • J. Radusiene
  • V. Jakstas
  • V. Janulis
  • G. Puodziuniene
  • A. Milasius
Article

Abstract

The qualitative and quantitative compositions of flavonoids (vicenin-2, luteolin-3′-di-O-glycoside, luteolin-7-O-glycoside, rutin, apigenin-7-O-glycoside, luteolin, apigenin) and chlorogenic acid in herb, leaves, and stems of yarrow (Achillea millefolium) samples collected in the Kaunas region of Lithuania have been studied by means of high-performance liquid chromatography (HPLC). It is established that these substances exhibit a characteristic distribution with predominant formation of apigenin-7-O-glycoside and luteolin-7-O-glycoside among the identified flavonoids in the herb of yarrow whereas the leaves contain predominantly chlorogenic acid, rutin, and apigenin-7-O-glycoside; the stems, predominantly chlorogenic acid, rutin, apigenin-7-O-glycoside, and luteolin-7-O-glycoside. The results can be used to choose selection donors of this medicinal plant material.

Keywords

Flavonoid Rutin Chlorogenic Acid Luteolin Apigenin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, Inc. 2008

Authors and Affiliations

  • R. Benetis
    • 1
  • J. Radusiene
    • 1
  • V. Jakstas
    • 1
  • V. Janulis
    • 1
  • G. Puodziuniene
    • 1
  • A. Milasius
    • 1
  1. 1.Kaunas University of MedicineKaunasLithuania

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