Pharmaceutical Chemistry Journal

, Volume 40, Issue 6, pp 325–328 | Cite as

Modification of chitosan by inclusion into interpolyelectrolyte complex with Eudragit L

  • R. I. Mustafin
  • A. A. Protasova
  • G. Van den Mooter
  • V. A. Kemenova


Interpolyelectrolyte complexes (IPECs) between chitosan (CTS) and Eudragit L100 have been obtained and characterized by turbidimetry, viscometry, and elemental analysis. The structure of the synthesized IPECs was studied using IR spectroscopy. The IPEC composition (defined as the component ratio, [CTS]/[L100]) depends on the molecular weight of CTS and amounts approximately to 1: 1 for medium-and high-molecular-weight CTS and to 1.25: 1 for low-molecular-weight CTS.


Chitosan Physical Mixture Methacrylic Acid Carboxy Group Polyelectrolyte Solution 
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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • R. I. Mustafin
    • 1
  • A. A. Protasova
    • 1
  • G. Van den Mooter
    • 2
  • V. A. Kemenova
    • 3
  1. 1.Kazan Medical UniversityKazan, TatarstanRussia
  2. 2.Leuven Catholical UniversityLeuvenBelgium
  3. 3.Research Center for Biomedical TechnologiesState Research Institute of Medicinal and Aromatic PlantsMoscowRussia

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