Pharmaceutical Chemistry Journal

, Volume 40, Issue 4, pp 202–205 | Cite as

Contraceptive properties of Saussurea salsa extract

  • A. I. Drab
  • E. N. Martynova
  • R. N. Pak
  • V. S. Triték
  • A. T. Kulyyasov
  • S. M. Adekenov


The spermicidal action of a Saussurea salsa (Pall.) Spreng. (SS) extract has been demonstrated by in vivo and in vitro tests in comparison to the reference preparation (Pharmatex). The SS extract in therapeutic concentrations did not produce significant irritating action on mucous membranes and had no negative influence on the normal genital microflora.


Sesquiterpene Lactone Vaginal Microflora Goryaev Chamber Contraceptive Property Irritant Action 


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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • A. I. Drab
    • 1
  • E. N. Martynova
    • 1
  • R. N. Pak
    • 1
  • V. S. Triték
    • 2
  • A. T. Kulyyasov
    • 2
  • S. M. Adekenov
    • 1
  1. 1.Institute of PhytochemistryMinistry of Education and Science of the Kazakhstan RepublicKaragandaKazakhstan
  2. 2.Karaganda State Medical AcademyKaragandaKazakhstan

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