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Distribution of radioactive iodine labeled sodium mercaptododecaborate in vivo in mice with melanoma B-16

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Abstract

The distribution of sodium mercaptododecaborate labeled with radioactive iodine (131I-BSH) in the organism of mice with melanoma B-16 was studied with the aid of a gamma camera. The 131I-BSH distribution in the whole organism coincides with that of its unlabeled analog. This result facilitates the solution of problems related to the planning and monitoring of boron neutron capture therapy.

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Authors and Affiliations

  1. Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk, Kaluga Region, Russia

    S. N. Koryakin, V. A. Yadrovskaya, A. P. Savina, S. E. Ul’yanenko & A. P. Baranov

Authors
  1. S. N. Koryakin
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  2. V. A. Yadrovskaya
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  3. A. P. Savina
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  4. S. E. Ul’yanenko
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  5. A. P. Baranov
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 39, No. 10, pp. 8–11, October, 2005.

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Koryakin, S.N., Yadrovskaya, V.A., Savina, A.P. et al. Distribution of radioactive iodine labeled sodium mercaptododecaborate in vivo in mice with melanoma B-16. Pharm Chem J 39, 514–517 (2005). https://doi.org/10.1007/s11094-006-0012-z

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  • DOI: https://doi.org/10.1007/s11094-006-0012-z

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