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Pharmaceutical Chemistry Journal

, Volume 39, Issue 9, pp 473–475 | Cite as

Synthesis and Anticholinesterase Activity of N-Oxyalkyl-substituted Pyridinium and Hydroquinolinium Salts and Their Isologs

  • A. G. Golikov
  • P. V. Reshetov
  • A. P. Kriven'ko
  • A. A. Safonova
Article

Abstract

N-oxyalkylpiperidines (perhydroquinolines), N-oxyalkylpyridinium (hydroquinolinium) salts, and oxazolo(oxazino)hydroquinolines obtained from 1,5-diketones and the products of their O-heterocyclization exhibit moderate anticholinesterase activity in comparison to that of galanthamine. The maximum inhibiting effect was observed for N-oxyalkylpyridinium salts.

Keywords

Organic Chemistry Pyridinium Maximum Inhibit Galanthamine Maximum Inhibit Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • A. G. Golikov
    • 1
  • P. V. Reshetov
    • 1
  • A. P. Kriven'ko
    • 1
  • A. A. Safonova
    • 1
  1. 1.Saratov State UniversitySaratovRussia

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