Origins of Life and Evolution of Biospheres

, Volume 44, Issue 4, pp 303–306 | Cite as

A New Start from Ground Zero?

  • Pier Luigi Luisi
Origin of Life


It is pointed out that one of the main reasons of lack of real conceptual progress in the field may lie in the fact that questions concerning the biogenesis of macromolecules have never been asked or addressed in a proper way. We should start again research on the origin of life starting from “ground zero” and focusing on the prebiotic synthesis of ordered sequences of proteins and nucleic acids.


Protein biogenesis Catalytic peptides His-Ser Proteases-first Prebiotic amino acids 


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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  1. 1.University of Rome3RomeItaly

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