Question 6: How Did Translation Occur?
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We have not yet reached a generally accepted view on how the genetic code might have originated. What has been proposed so far? The main part of the contribution to the panel discussion was devoted to recall to the audience the chronological order of publications the main aim of which it was, at least theoretically, to somehow connect physico-chemical properties of physically proximal ‘universal adapters’, usually some kind of nucleic acid polymer, with reactive forms of physically proximal amino acids that would subsequently polymerise into polypeptides.
KeywordsGenetic code Translation Peptidyl-RNA Peptidyl transfer Amphiphiles
The financial support through the Ettore Majorana Foundation of the 4th course of the Scuola Internazionale sulla Complessità on the Basic Questions on the Origin of Life and of its panel discussion contributors is gratefully acknowledged.
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