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Randomized Clinical Stroke Rehabilitation Trials in 2005

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Abstract

This article reviews randomized control trials (RCTs) undertaken in stroke rehabilitation in the year 2005. A Medline search generated 31 RCTs in stroke rehabilitation in the year 2005 in the English language. These trials were primarily efficacy studies of a number of treatments: medications such as folate, vitamin B12 and bisphosphonates in preventing osteoporotic related hip fractures, compression stockings in preventing deep vein thrombosis (DVT), use of mechanical robots and positioning of the upper limb to help improve function; and, transcranial magnetic coil stimulation, acupuncture and neural tissue transplant to enhance motor recovery in post-stroke patients.

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References

  1. Mayo NE, Wood-Dauphinee S, Cote R, Gayton D, Carlton J, Buttery J, Tamblyn R (2000) There’s no place like home: an evaluation of early supported discharge for stroke. Stroke 31(5):1016–1023

    PubMed  CAS  Google Scholar 

  2. Thorsen AM, Holmqvist LW, de Pedro-Cuesta J, von Koch L (2005) A randomized controlled trial of early supported discharge and continued rehabilitation at home after stroke: five-year follow-up of patient outcome. Stroke 36(2):297–303

    Article  PubMed  Google Scholar 

  3. Fjaertoft H, Indredavik B, Magnussen J, Johnsen R (2005) Early supported discharge for stroke patients improves clinical outcome. Does it also reduce use of health services and costs? One-year follow-up of a randomized controlled trial. Cerebrovasc Dis 19(6):376–383

    Article  PubMed  Google Scholar 

  4. Grasel E, Biehler J, Schmidt R, Schupp W (2005) Intensification of the transition between inpatient neurological rehabilitation and home care of stroke patients. Controlled clinical trial with follow-up assessment six months after discharge. Clin Rehabil 19(7):725–736

    Article  PubMed  CAS  Google Scholar 

  5. Dey P, Woodman M, Gibbs A, Steele R, Stocks SJ, Wagstaff S, Khanna V, Chaudhuri MD (2005) Early assessment by a mobile stroke team: a randomised controlled trial. Age Ageing 34(4):331–338

    Article  PubMed  Google Scholar 

  6. Kondziolka D, Steinberg GK, Wechsler L, Meltzer CC, Elder E, Gebel J, Decesare S, Jovin T, Zafonte R, Lebowitz J, Flickinger JC, Tong D, Marks MP, Jamieson C, Luu D, Bell-Stephens T, Teraoka J (2005) Neurotransplantation for patients with subcortical motor stroke: a phase 2 randomized trial. J Neurosurg 103(1):38–45

    Article  PubMed  Google Scholar 

  7. Khedr EM, Ahmed MA, Fathy N, Rothwell JC (2005) Therapeutic trial of repetitive transcranial magnetic stimulation after acute ischemic stroke. Neurology 65:466–468

    Article  PubMed  Google Scholar 

  8. Takeuchi N, Chuma T, Matsuo Y, Watanabe I, Ikoma K (2005) Repetitive transcranial magnetic stimulation of contralesional primary motor cortex improves hand function after stroke. Stroke 36(12):2681–2686

    Article  PubMed  Google Scholar 

  9. Mansur CG, Fregni F, Boggio PS, Riberto M, Gallucci-Neto J, Santos CM, Wagner T, Rigonatti SP, Marcolin MA, Pascual-Leone A (2005) A sham stimulation-controlled trial of rTMS of the unaffected hemisphere in stroke patients. Neurology 64(10):1802–1804

    Article  PubMed  CAS  Google Scholar 

  10. Sze FK, Wong E, Or KK, Lau J, Woo J (2002) Does acupuncture improve motor recovery after stroke? A meta-analysis of randomized controlled trials. Stroke 33(11):2604–2619

    Article  PubMed  Google Scholar 

  11. Wu H, Tang J, Lin X, Lau J, Leung P, Woo J, Li Y (2006) Acupuncture for stroke rehabilitation. Cochrane Database Syst Rev 3:CD004131

  12. Park J, White AR, James MA, Hemsley AG, Johnson P, Chambers J, Ernst E (2005) Acupuncture for subacute stroke rehabilitation: a Sham-controlled, subject- and assessor-blind, randomized trial. Arch Intern Med 165(17):2026–2031

    Article  PubMed  Google Scholar 

  13. Wayne PM, Krebs DE, Macklin EA, Schnyer R, Kaptchuk TJ, Parker SW, Scarborough DM, McGibbon CA, Schaechter JD, Stein J, Stason WB (2005) Acupuncture for upper-extremity rehabilitation in chronic stroke: a randomized sham-controlled study. Arch Phys Med Rehabil 86(12):2248–2255

    Article  PubMed  Google Scholar 

  14. van der Lee JH, Snels IA, Beckerman H, Lankhorst GJ, Wagenaar RC, Bouter LM (2001) Exercise therapy for arm function in stroke patients: a systematic review of randomized controlled trials. Clin Rehabil 15(1):20–31

    Article  PubMed  Google Scholar 

  15. Hesse S, Werner C, Pohl M, Rueckriem S, Mehrholz J, Lingnau ML (2005) Computerized arm training improves the motor control of the severely affected arm after stroke: a single-blinded randomized trial in two centers. Stroke 36(9):1960–1966

    Article  PubMed  CAS  Google Scholar 

  16. Chen JC, Liang CC, Shaw FZ (2005) Facilitation of sensory and motor recovery by thermal intervention for the hemiplegic upper limb in acute stroke patients: a single-blind randomized clinical trial. Stroke 36(12):2665–2669

    Article  PubMed  Google Scholar 

  17. Ada L, Goddard E, McCully J, Stavrinos T, Bampton J (2005) Thirty minutes of positioning reduces the development of shoulder external rotation contracture after stroke: a randomized controlled trial. Arch Phys Med Rehabil 86(2):230–234

    Article  PubMed  Google Scholar 

  18. Jones A, Tilling K, Wilson-Barnett J, Newham DJ, Wolfe CD (2005) Effect of recommended positioning on stroke outcome at six months: a randomized controlled trial. Clin Rehabil 19(2):138–145

    Article  PubMed  CAS  Google Scholar 

  19. Desrosiers J, Bourbonnais D, Corriveau H, Gosselin S, Bravo G (2005) Effectiveness of unilateral and symmetrical bilateral task training for arm during the subacute phase after stroke: a randomized controlled trial. Clin Rehabil 19(6):581–593

    Article  PubMed  Google Scholar 

  20. Turton AJ, Britton E (2005) A pilot randomized controlled trial of a daily muscle stretch regime to prevent contractures in the arm after stroke. Clin Rehabil 19(6):600–612

    Article  PubMed  Google Scholar 

  21. Platz T, Eickhof C, van Kaick S, Engel U, Pinkowski C, Kalok S, Pause M (2005) Impairment-oriented training or Bobath therapy for severe arm paresis after stroke: a single-blind, multicentre randomized controlled trial. Clin Rehabil 19(7):714–724

    Article  PubMed  CAS  Google Scholar 

  22. Chae J, Yu DT, Walker ME, Kirsteins A, Elovic EP, Flanagan SR, Harvey RL, Zorowitz RD, Frost FS, Grill JH, Fang ZP (2005) Intramuscular electrical stimulation for hemiplegic shoulder pain: a 12-month follow-up of a multiple-center, randomized clinical trial. Am J Phys Med Rehabil 84(11):832–842

    Article  PubMed  Google Scholar 

  23. Salbach NM, Mayo NE, Robichaud-Ekstrand S, Hanley JA, Richards CL, Wood-Dauphinee S (2005) The effect of a task-oriented walking intervention on improving balance self-efficacy poststroke: a randomized, controlled trial. J Am Geriatr Soc 53(4):576–582

    Article  PubMed  Google Scholar 

  24. You SH, Jang SH, Kim YH, Hallett M, Ahn SH, Kwon YH, Kim JH, Lee MY (2005) Virtual reality-induced cortical reorganization and associated locomotor recovery in chronic stroke: an experimenter-blind randomized study. Stroke 36(6):1166–1171

    Article  PubMed  Google Scholar 

  25. Yang YR, Yen JG, Wang RY, Yen LL, Lieu FK (2005) Gait outcomes after additional backward walking training in patients with stroke: a randomized controlled trial. Clin Rehabil 19(3):264–273

    Article  PubMed  Google Scholar 

  26. Bagley P, Hudson M, Forster A, Smith J, Young J (2005) A randomized trial evaluation of the Oswestry Standing Frame for patients after stroke. Clin Rehabil 19(4):354–364

    Article  PubMed  Google Scholar 

  27. Ramnemark A, Nilsson M, Borssen B, Gustafson Y (2000) Stroke, a major and increasing risk factor for femoral neck fracture. Stroke 31:1572–1577

    PubMed  CAS  Google Scholar 

  28. Ramnemark A, Nyberg L, Borssen B, Olsson T, Gustafson Y (1998) Fractures after stroke. Osteoporos Int 8:92–95

    Article  PubMed  CAS  Google Scholar 

  29. Mulley G, Espley AJ (1979) Hip fracture after hemiplegia. Postgrad Med J 55(642):264–265

    Article  PubMed  CAS  Google Scholar 

  30. Sato Y, Honda Y, Iwamoto J, Kanoko T, Satoh K (2005) Effect of folate and mecobalamin on hip fractures in patients with stroke: a randomized controlled trial. JAMA 293(9):1082–1088

    Article  PubMed  CAS  Google Scholar 

  31. Sato Y, Iwamoto J, Kanoko T, Satoh K (2005) Risedronate therapy for prevention of hip fracture after stroke in elderly women. Neurology 64(5):811–816

    PubMed  CAS  Google Scholar 

  32. Sato Y, Iwamoto J, Kanoko T, Satoh K (2005) Low-dose vitamin D prevents muscular atrophy and reduces falls and hip fractures in women after stroke: a randomized controlled trial. Cerebrovasc Dis 20(3):187–192

    Google Scholar 

  33. Studenski S, Duncan PW, Perera S, Reker D, Lai SM, Richards L (2005) Daily functioning and quality of life in a randomized controlled trial of therapeutic exercise for subacute stroke survivors. Stroke 36(8):1764–1770

    Article  PubMed  Google Scholar 

  34. Macko RF, Ivey FM, Forrester LW, Hanley D, Sorkin JD, Katzel LI, Silver KH, Goldberg AP (2005) Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke: a randomized, controlled trial. Stroke 36(10):2206–2211

    Article  PubMed  Google Scholar 

  35. Pang MY, Eng JJ, Dawson AS, McKay HA, Harris JE (2005) A community-based fitness and mobility exercise program for older adults with chronic stroke: a randomized, controlled trial. J Am Geriatr Soc 53(10):1667–1674

    Article  PubMed  Google Scholar 

  36. Akinwuntan AE, De Weerdt W, Feys H, Pauwels J, Baten G, Arno P, Kiekens C (2005) Effect of simulator training on driving after stroke: a randomized controlled trial. Neurology 65(6):843–850

    Article  PubMed  CAS  Google Scholar 

  37. Lacut K, Bressollette L, Le Gal G, Etienne E, De Tinteniac A, Renault A, Rouhart F, Besson G, Garcia JF, Mottier D, Oger E (2005) VICTORIAh (Venous Intermittent Compression and Thrombosis Occurrence Related to Intra-cerebral Acute hemorrhage) Investigators. Prevention of venous thrombosis in patients with acute intracerebral hemorrhage. Neurology 65(6):865–869

    Article  PubMed  CAS  Google Scholar 

  38. Pennington L, Roddam H, Burton C, Russell I, Godfrey C, Russell D (2005) Promoting research use in speech and language therapy: a cluster randomized controlled trial to compare the clinical effectiveness and costs of two training strategies. Clin Rehabil 19(4):387–397

    Article  PubMed  Google Scholar 

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  1. Burke Rehabilitation Hospital, Weill Medical College of Cornell University, 785 Mamaroneck Ave., White Plains, NY, 10605, USA

    Meheroz H. Rabadi

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  1. Meheroz H. Rabadi
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Correspondence to Meheroz H. Rabadi.

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Special issue dedicated to John P. Blass.

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Rabadi, M.H. Randomized Clinical Stroke Rehabilitation Trials in 2005. Neurochem Res 32, 807–821 (2007). https://doi.org/10.1007/s11064-006-9211-y

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  • DOI: https://doi.org/10.1007/s11064-006-9211-y

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