, Volume 47, Issue 3, pp 244–247 | Cite as

F-Wave in the Upper Extremities of Patients with Primary Torsion Dystonia

  • N. Semerdjieva
  • D. Atanasova
  • G. Hranov
  • I. Milanov

We investigated characteristics of the F-waves in the upper limbs of patients suffering from primary torsion dystonia (PTD) by means of surface-electrode electromyography. Single electric stimulation was used to obtain optimum M-responses from the m. abductor pollicis brevis (median nerve) and m. abductor digiti minimi (ulnar nerve). Ten consecutive supramaximum electrical stimuli were applied to each nerve to obtain F-waves from the wrist. In general, the registered M-response latencies and amplitudes, as well as conduction velocities via all inspected nerves, demonstrated no significant deviations from the normal ranges. Nearly all investigated patients, except one, had normal F-wave minimal latencies. The mean amplitudes of F-waves from both median and ulnar nerves were higher than the average F-wave amplitudes described in the literature. The frequency of occurrence of F-waves in both median and ulnar nerves was greater than in the norm. According to our results, it can be concluded that the amplitude and, to some extent, frequency rather than the latency of F-waves are important in the studies of patients with PTD. Increased amplitudes and frequencies reveal changes in the excitability of alpha motoneurons, which could be accepted as a measure of a disturbed interneuronal balance probably caused by alterations in the suprasegmental control mechanisms related to PTD.


surface electromyography F-wave upper extremities primary torsion dystonia latency amplitude frequency of occurrence 


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  1. 1.
    J. Jankovic and S. Fahn, “Dystonic disorders,” in: Parkinson’s Disease and Movement Disorders, J. Jankovic, E. Tolosa (eds.), Lippincott, Williams and Wilkins (2002), pp. 331-351.Google Scholar
  2. 2.
    T. Warner, “Dystonia,” in: Birmingham Movement Disorders Course, Mov. Disord. Soc., (2008), pp. 267-279.Google Scholar
  3. 3.
    A. Albanese, M. P. Barnes, K. P. Bhatia, et al., “A systematic review on the diagnosis and treatment of primary (idiopathic) dystonia and dystonia plus syndromes: report of an EFNS/MDS-ES Task Force,” Eur. J. Neurol., 13, No. 5, 433-444 (2006).CrossRefPubMedGoogle Scholar
  4. 4.
    M. A. Fisher, “Are H reflexes and F responses equally sensitive to changes in motoneuronal excitability?” Muscle Nerve, 19, No. 10, 1345-1346 (1996).CrossRefPubMedGoogle Scholar
  5. 5.
    M. A. Fisher, “H reflexes and F waves: physiology and clinical indications,” Muscle Nerve, 15, No. 11, 1223-1233 (1992).CrossRefPubMedGoogle Scholar
  6. 6.
    M. G. Espiritu, C. S. Lin, and D. Burke, “Motoneuron excitability and the F wave,” Muscle Nerve, 27, No. 6, 720-727 (2003).CrossRefPubMedGoogle Scholar
  7. 7.
    B. Ishpekova, I. Milanov, and L. Hristova, Clinical Electromyography [in Bulgarian], Unison Art, Sofia (2003).Google Scholar
  8. 8.
    J. Кimura, Electrodiagnosis in Diseases of Nerve and Muscle. Principles and Practice, Edit. 3, Oxford Univ. Press (2001).Google Scholar
  9. 9.
    H. Matsumoto and Y. Ugawa, “Clinical signs, neurophysiological evaluation, and medication of spasticity - review,” Brain Nerve, 60, No. 12, 1409-1414 (2008).PubMedGoogle Scholar
  10. 10.
    B. Fierro, D. Raimondo, and A. Modica, “Analysis of F response in upper motoneurone lesions,” Acta Neurol. Scand., 82, No. 5, 329-334 (1990).CrossRefPubMedGoogle Scholar
  11. 11.
    M. A. Fisher, “The contemporary role of F-wave studies. F-wave studies: clinical utility,” Muscle Nerve, 21, No. 8, 1098-1101 (1998).CrossRefPubMedGoogle Scholar
  12. 12.
    K. Wohlfarth, M. Schubert, B. Rothe, et al., “Remote F-wave changes after local botulinum toxin application,” Clin. Neurophysiol., 112, No. 4, 636-640 (2001).CrossRefPubMedGoogle Scholar
  13. 13.
    J. Dressnandt, C. Auer, and B. Conrad, “Influence of baclofen upon the alpha-motoneurons in spasticity by means of F-wave analysis,” Muscle Nerve, 18, No. 1, 103-107 (1995).CrossRefPubMedGoogle Scholar
  14. 14.
    I. Milanov, “Mechanisms of baclofen action on spasticity,” Acta Neurol. Scand., 85, 305-310 (1992)CrossRefPubMedGoogle Scholar
  15. 15.
    I. Milanov, “Mechanisms of tetrazepam action on spasticity,” Acta Neurol. Belg., 85, No. 5, 305-310 (1992).CrossRefGoogle Scholar
  16. 16.
    I. Milanov and D. Georgiev, “Mechanisms of tizanidine action on spasticity,” Acta Neurol. Scand., 89, No. 4, 274-279 (1994).CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • N. Semerdjieva
    • 1
  • D. Atanasova
    • 1
  • G. Hranov
    • 1
  • I. Milanov
    • 1
  1. 1.UMHATNP “St. Naum,”SofiaBulgaria

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