Journal of Neuro-Oncology

, Volume 102, Issue 1, pp 115–119 | Cite as

Coexisting cranial and multiple spinal meningioma in a child-report of a case

  • Sujeet Kumar Shukla
  • Adarsh Trivedi
  • Vivek Sharma
  • Kulwant Singh
Clinical Study - Patient Studies


Von Ricklinghausen’s disease is commonly associated with simultaneous cranial and spinal meningioma but these are not true meningiomas. Craniospinal meningiomas without Von Ricklinghausen’s disease are very rare. We report a 13-year-old girl who presented with two episodes of right focal seizure with secondary generalisation of three year’s duration, weakness of both lower limbs for 6 months, and retention of urine of three month’s duration. MRI brain showed enhancing lesion in the left fronto-parietal region. MRI spine revealed enhancing intradural extramedullary lesion at D4-5, D9-10, and L1-2. The tumours were excised completely in a single stage, first by craniotomy then by multi level laminectomy. On histology the spinal meningioma had predominant meningothiliomatous. We followed up for 6 months and the patient recovered with power grade 4/5 both lower limb.


Fronto-parietal supratentorial Extradural Synchronous meningiomas 


  1. 1.
    Anfimow J, Blumenau L (1889) Ein Fall multipler Geschwulste in der Schadelhohle. Neurologisches Zentralblatt 8:585Google Scholar
  2. 2.
    Arseni C, Dumitrescu IL, Carp N (1984) Orbital, sphenoidal ridge and spinal meningiomas occurring in one patient. Neurochirurgia (Stuttg) 27:84–86Google Scholar
  3. 3.
    Canale D, Bebin J, Knigton RS (1964) Neurologic manifestations of von Recklinghausen’s disease of the nervous system. Confin Neurol 24:359–403CrossRefPubMedGoogle Scholar
  4. 4.
    Cushing H, Eisenhardt L (1938) Meningiomas. Their classification, regional behaviour, life history and surgical end results. CC Thomas, Springfield, 785 ppGoogle Scholar
  5. 5.
    Dorizzi A, Crivelli G, Marra A et al (1992) Associated cervical schwannoma and dorsal meningioma. Case report and review of the literature. J Neurosurg Sci 36:173–176PubMedGoogle Scholar
  6. 6.
    Elvidge R (1981) Central neurofibromatosis with bilateral acoustic neuroma. Adv Neurol 29:57–65Google Scholar
  7. 7.
    Hoffmann GT, Earle KM (1960) Meningiomas with malignant transformation and implantation in the subarachnoid space. J Neurosurg 17:486–492CrossRefPubMedGoogle Scholar
  8. 8.
    Ilgren EB, Kinnier-Wilson LM, Stiller CA (1985) Gliomas in neurofibromatosis: a series of 89 cases with evidence for enhanced malignancy in associated cerebellar astrocytomas. Pathol Annu 20:331–358PubMedGoogle Scholar
  9. 9.
    Kannuki S, Soga T, Hondo H et al (1991) Coexistence of intracranial and spinal meningiomas—report of two cases. Neurol Med Chir (Tokyo) 31:720–724CrossRefGoogle Scholar
  10. 10.
    Lee M, Rezai AR, Freed D et al (1996) Intramedullary spinal cord tumors in neurofibromatosis. Neurosurgery 38:32–37CrossRefPubMedGoogle Scholar
  11. 11.
    Mufson JA, Davidoff LM (1944) Multiple meningiomas. Report of two cases. J Neurosurg 1:45–47CrossRefGoogle Scholar
  12. 12.
    Nahser HC, Grote W, Lohr E, Gerhard L (1981) Multiple menigiomas. Clinical and computed tomographic observations. Neuroradiology 21:259–263CrossRefPubMedGoogle Scholar
  13. 13.
    Nishiura I, Koyama T, Tanaka K et al (1989) The occurrence of different types of spinal tumours in one patient. A case report and review of the literature. Neurochirurgia 32:52–55PubMedGoogle Scholar
  14. 14.
    Nittner K (1976) Spinal meningiomas, neurinomas and neurofibromas and hourglass tumors. In: Vinken PJ, Bruyan GW (eds) Handbook of clinical neurology, vol 20. North-Holland, Amsterdam, pp 177–322Google Scholar
  15. 15.
    O’Neill P, Booth AE (1984) Multiple meningiomas. Surg Neurol 21:80–82CrossRefPubMedGoogle Scholar
  16. 16.
    Radley MG, McDonald JV (1992) Meningeal hemangiopericytoma of the posterior fossa and thoracic epidural space. A case report. Neurosurgery 30:446–452CrossRefPubMedGoogle Scholar
  17. 17.
    Roda JM, Benscosme JA, Perez-Higueras A, Fraile M (1992) Simultaneous multiple intracranial and spinal meningiomas. Neurochirurgia (Stuttg) 35:92–94Google Scholar
  18. 18.
    Rodriguez HA, Berthrong M (1966) Multiple primary intracranial tumours in von Recklinghausen’s neurofibromatosis. Arch Neurol 14:467–475PubMedGoogle Scholar
  19. 19.
    Sedzimir CB, Frazer AK, Roberts JR (1973) Cranial and spinal meningioma in a pair of twin boys. J Neurol Neurosurg Psych 35:368CrossRefGoogle Scholar
  20. 20.
    The Committee of Brain Tumor Registry in Japan: Brain Tumor Registry in Japan, vol 6. 1987, 175 ppGoogle Scholar
  21. 21.
    Weil SM, Gewirtz RJ, Tew JM Jr (1990) Concurrent intradural and extradural meningiomas of the cervical spine. Neurosurgery 27:629–631CrossRefPubMedGoogle Scholar
  22. 22.
    Zervas NT, Shintani A, Kallar B, Berry RG (1970) Multiple meningiomas occupying separate neuraxial compartments. J Neurosurg 33:216–220CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC. 2010

Authors and Affiliations

  • Sujeet Kumar Shukla
    • 1
  • Adarsh Trivedi
    • 1
  • Vivek Sharma
    • 1
  • Kulwant Singh
    • 1
  1. 1.Department of Neurosurgery, Institute of Medical SciencesBanaras Hindu UniversityVaranasiIndia

Personalised recommendations