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Journal of Neuro-Oncology

, Volume 79, Issue 3, pp 255–258 | Cite as

Primary midbrain cystic germinoma mimicking glioma: a case with neuroendoscopic biopsy

  • Masafumi Uchino
  • Daisuke Haga
  • Toshiaki Mito
  • Tohru Kuramitsu
  • Noriko Nakamura
Laboratory investigation

Summary

Intracranial germinoma arising primarily in the midbrain is extremely rare. We present the first reported case of cystic midbrain germinoma that lacked evident solid components and mimicked a midbrain glioma. In a 22-year-old man with headache and diplopia, magnetic resonance imaging showed a ring-enhancing lesion in the midbrain. The preoperative diagnosis included brain stem glioma, metastasis, and neuroepithelial cyst. A neuroendoscopic biopsy specimen provided a histologic diagnosis of germinoma. The patient responded well to chemotherapy and radiotherapy. The case illustrates the diagnostic value of neuroendoscopic biopsy in the differential diagnosis of brainstem lesions in adult. The possibilities considered should now include germinoma.

Keywords

cyst germinoma glioma midbrain neuroendoscopy 

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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Masafumi Uchino
    • 1
  • Daisuke Haga
    • 1
  • Toshiaki Mito
    • 1
  • Tohru Kuramitsu
    • 1
  • Noriko Nakamura
    • 2
  1. 1.Department of NeurosurgerySaiseikai Yokohama-shi Nambu HospitalKanagawa-kenJapan
  2. 2.Department of PathologySaiseikai Yokohama-shi Nambu Hospital,YokohamaJapan

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