Journal of Neuro-Oncology

, Volume 74, Issue 2, pp 179–181 | Cite as

Huge Bilateral Pulmonary and Pleural Metastasis from Intracranial Meningioma: A Case Report and Review of the Literature

  • Tahsin Erman
  • İsmail Hanta
  • Sebahattin Hacıyakupoğlu
  • Suzan Zorludemir
  • Handan Zeren
  • A. İskender Göçer
Clinical Study


A case of recurrent meningioma with atypical features and extracranial metastases is reported. A 34-year-old female was operated in 1996, 2000, and 2002, and frontal parasagital meningioma was extirpated. Histological diagnoses of all the resected tumors were meningotheliomatous meningioma, WHO Grade I. However, 2 years later, the tumor recurred in the frontal scalp and was removed again totally. Histological diagnosis was reported as an atypical meningioma; meningotheliomatous type; WHO Grade II. She received radiation therapy. But the tumor had metastasized to the lung and pleura. Transthoracic tru-cut biopsy was performed from large mass of the left lung. Cytopathology was consistent with malignant meningioma, metastasis from the patient’s known intracranial meningioma. Ki-67 staining index at the primary and metastatic sites of the present cases were 7 and 5%, respectively. We reviewed and discussed the histopathological features and mechanisms of metastasizing meningioma.


lung meningioma metastasis pleura 


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Copyright information

© Springer 2005

Authors and Affiliations

  • Tahsin Erman
    • 1
  • İsmail Hanta
    • 2
  • Sebahattin Hacıyakupoğlu
    • 1
  • Suzan Zorludemir
    • 3
  • Handan Zeren
    • 3
  • A. İskender Göçer
    • 1
  1. 1.Department of NeurosurgeryÇukurova University School of MedicineBalcalıTurkey
  2. 2.Chest DiseaseÇukurova University, School of MedicineAdanaTurkey
  3. 3.Department of PathologyÇukurova University, School of MedicineAdanaTurkey

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