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Synergistic Application of Zinc and Vitamin C to Support Memory and Attention and to Decrease the Risk of Developing Nervous System Diseases

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Provision of the body with zinc and vitamin C is important for CNS functioning. Zinc ions take part in neurotransmission (transmission of signals from acetylcholine, catecholamine, serotonin, and prostaglandin receptors) and in ubiquitin-dependent protein degradation. Zinc deficiency is associated with the development of Alzheimer’s disease and depression. Zinc supplementation (10–30 mg/day) improves neurological recovery in patients with stroke and closed craniocerebral injury and also improves measures of attention; it decreases hyperactivity in children. Vitamin C is a synergist of zinc which supports the antioxidant resources of the brain, synaptic activity, and detoxification. Vitamin C supplements at a dose of 130–500 mg/day are recommended for the prophylaxis of dementia and neurodegenerative pathology.

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Authors and Affiliations

  1. Ivanovo State Medical Academy, Ministry of Health of the Russian Federation, Ivanovo, Russia

    O. A. Gromova, A. V. Pronin & M. A. Kilchevsky

  2. Moscow Institute of Physics and Technology (State University), Dolgoprudnyi, Russia

    I. Yu. Torshin

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  1. O. A. Gromova
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  2. I. Yu. Torshin
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  3. A. V. Pronin
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  4. M. A. Kilchevsky
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Correspondence to O. A. Gromova.

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Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 117, No. 7, Iss. 1, pp. 112–119, July, 2017.

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Gromova, O.A., Torshin, I.Y., Pronin, A.V. et al. Synergistic Application of Zinc and Vitamin C to Support Memory and Attention and to Decrease the Risk of Developing Nervous System Diseases. Neurosci Behav Physi 49, 357–364 (2019). https://doi.org/10.1007/s11055-019-00740-0

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