Effects of Conditioned Reflex Retraining Regime on Search Behavior in a Radial Maze in Rats
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Experiments on rats showed that sessions of retraining to find a new preferred reinforcement location in a radial maze, continuously repeated on the experimental day, led to impairment of the animals’ ability to use navigational orientation as the most adaptive tactic for maximizing reinforcement, with retention of less productive conditioned reflex responding to the presentation of signals within the maze. Some series of experiments showed that sleep had an adaptive role, including sleep induced by somnogenic neuropeptides, and was needed for the experimental animals to perform the behavioral task successfully in conditions of heightened emotional tension and to prevent any possible neurological disorders.
Keywordsspatial orientation retraining adaptive functions of sleep
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- 1.S. V. Al’bertin, “Involvement of the nucleus accumbens in forming spatial selection responses in rats in a radial maze,” Ros. Fiziol. Zh., 88, No. 5, 545–552 (2002).Google Scholar
- 2.S. V. Albertin and S. I. Wiener, “Neuronal activity of the nucleus accumbens and hippocampus in rats on formation of seeking behavior in a radial maze,” Byull. Eksperim. Biol. Med., 158, No. 10, 400–406 (2014).Google Scholar
- 3.S. V. Albertin, “Diagnosis of attention deficit hyperactivity syndrome,” Zh. Nevrol. Psikhiat., No. 12, 67–73 (2010).Google Scholar
- 4.M. M. Bogoslovskii and S. V. Al’bertin, “Effects of emotional stress on the nature of sleep in cats,” Zh. Vyssh. Nerv. Deyat., 29, No. 3, 557–565 (1979).Google Scholar
- 5.I. G. Karmanov, V. F. Maksimuk, I. B. Borisov, et al., “Analysis of the actions of delta sleep-inducing peptide in cats and white mice,” Zh. Evolyuts. Biokhim. Fiziol., 15, No. 6, 583–589 (1979).Google Scholar
- 6.M. M. Khananashvili, “Biologically positive and negative psychogenic (informational) stress,” in: Dysregulatory Pathology, Meditsina, Moscow (2002).Google Scholar
- 8.S. V. Albertin, R. Shibata, E. Tabichi, et al., “Functional properties of nucleus accumbens neurons in zones receiving hippocampal or prefrontal cortical inputs: The Spatial and Behavioral Correlates,” in: Proc. 2nd Int. Conf. on Cognitive Sciences, St. Petersburg (2006), pp. 151–152.Google Scholar
- 13.L. S. Gellerman, “Chance orders of alternating stimuli in visual discrimination experiments,” Gen. Psychol., 42, 206 (1933).Google Scholar
- 16.M. Klanker, M. Feenstra, and D. Denys, “Dopaminergic control of cognitive flexibility in humans and animals,” Front. Neurosci., Art. 201 (2013), doi: https://doi.org/10.3389/fnins.2013.00201.