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Neuroscience and Behavioral Physiology

, Volume 48, Issue 2, pp 157–165 | Cite as

Structural Aspects of the Involvement of the Brainstem Nuclei in the Processing of Functionally Diverse Information Streams Passing through the Basal Ganglia

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The structural basis for information processing in the morphofunctional system of the basal ganglia is considered on the basis of analysis of retrograde axonal transport studies of the projections between functionally diverse parts of the brainstem nuclei and functionally diverse segments of basal ganglia structures. The organization of projections between these structures in the dog brain revealed topical elements pointing to the possibility of the segregated transmission of information between the limbic and motor segments of the brainstem nuclei and the corresponding areas of the basal ganglia. However, these projection systems are dominated by convergent transmission of functionally diverse information, providing evidence that information of different modalities may be integrated not solely in the main, but in all the nuclei of the morphofunctional basal ganglia system. Labeled sparsely branched long-axon “reticular” neurons in the brainstem nuclei projecting to the basal ganglia also provide evidence of the integrative function of the nuclei of interest. The possibility that these data could be used to create new models helping us to understand the functioning of the basal ganglia in health and disease is discussed.

Keywords

basal ganglia zone incerta rostromedial tegmental nucleus deep mesencephalic nucleus peripeduncular nucleus pedunculopontine nucleus 

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Pavlov Institute of Physiology, Russian Academy of SciencesSt. PetersburgRussia

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