The effects of sleep deprivation produced using a carousel method on the consolidation of spatial memory were studied in rats (male Wistar rats) after one-day training using the Frick et al. protocol (2000) in a Morris water maze. Data were obtained providing evidence that the memory trace after rapid 3-h training was retained for one day. Sleep deprivation for 24 h after training prevented reinforcement (consolidation) of spatial memory. The results led to the conclusion that a model based on one-day training can be used to study the neurophysiological and neurochemical mechanisms of the effects of sleep deprivation on consolidation of spatial memory.
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Translated from Zhurnal Vysshei Nervnoi Deyatel’nosti imeni I. P. Pavlova, Vol. 61, No. 3, pp. 322–331, May–June, 2011.
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Dorokhov, V.B., Kozhedub, R.G., Arseniev, G.N. et al. Effects of Sleep Deprivation on Consolidation of Spatial Memory in Rats after One-Day Training in a Morris Water Maze. Neurosci Behav Physi 42, 1032–1039 (2012). https://doi.org/10.1007/s11055-012-9675-y
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DOI: https://doi.org/10.1007/s11055-012-9675-y