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Neuroscience and Behavioral Physiology

, Volume 38, Issue 2, pp 171–179 | Cite as

Activity of rabbit neocortex and hippocampus neurons in orientational-investigative behavior and freezing

  • I. V. Pavlova
  • G. L. Vanetsian
Article
  • 43 Downloads

Abstract

Autocorrelation histograms were used to study the nature of spike activity in neurons recorded bilaterally from the visual and parietal areas of the cortex and hippocampal field CA1 in rabbits in free behavior during exposure to emotionally significant stimuli. Active movement orientational-investigative reactions to stimuli were associated with grouping of discharges and periodicity in the spike activity of most neurons in the cortex and hippocampus, this being dominated by the θ frequency (predominantly 4–5 Hz in the cortex and 4–5 and 6–7 Hz in the hippocampus). As compared with active movement reactions, freezing in response to stimulation was associated with increased numbers of neurons with uniform discharge distributions, while the spike activity of neurons with discharge periodicity showed increases in the intensity of the δ frequency (predominantly from 2 to 4 Hz), while θ intensity decreased. The number of neurons with periodic frequency in the δ range was greater in freezing than in the baseline state of calmly sitting rabbits.

Key words

orientational-investigative behavior freezing neuron neocortex hippocampus 

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References

  1. 1.
    V. L. Bianki, Brain Asymmetry in Animals [in Russian], Nauka, Leningrad (1985).Google Scholar
  2. 2.
    A. V. Bogdanov and A. G. Galashina, “Comparative analysis of the spike frequencies of neurons in the sensorimotor cortex of the right and left hemispheres in rabbits during immobilization catatonia,” Zh. Vyssh. Nerv. Deyat., 52, No. 4, 489–494 (2002).Google Scholar
  3. 3.
    O. S. Vinogradova, The Hippocampus and Memory [in Russian], Nauka, Moscow (1975).Google Scholar
  4. 4.
    G. V. Georgiev, “Ratio of slow (tension rhythm) and spike activity in the electrocorticogram of the rabbit,” Zh. Vyssh. Nerv. Deyat., 16, No. 1, 76–81 (1966).Google Scholar
  5. 5.
    D. A. Zhukov, Psychogenic Stress. Behavioral and Endocrine Correlates of Genetic Determinants of Stress Reactivity in Uncontrollable Situations [in Russian], St. Petersburg Center for Scientific and Technical Information, St. Petersburg (1997).Google Scholar
  6. 6.
    N. N. Kudryavtseva, I. V. Bakshtanovskaya, and N. K. Popova, “Catatonia as an element in submissive behavior of mice intraspecies agonistic interactions,” Zh. Vyssh. Nerv. Deyat., 39, No. 1, 128–135 (1989).Google Scholar
  7. 7.
    M. N. Livanov, Spatial Organization of Brain Processes [in Russian], Nauka, Moscow (1972).Google Scholar
  8. 8.
    I. V. Pavlova, “Spike activity of individual cortical neurons in rabbits in natural food motivation,” Zh. Vyssh. Nerv. Deyat., 46, No. 6, 1210–1214 (1995).Google Scholar
  9. 9.
    I. V. Pavlova, “Spike activity of neurons in the amygdala and hypothalamus recorded bilaterally in food motivation,” Zh. Vyssh. Nerv. Deyat., 54, No. 6, 776–784 (2004).Google Scholar
  10. 10.
    I. V. Pavlova, I. P. Levshina, G. L. Vanetsian, Yu. V. Pavlov, N. N. Shuikin, and E. A. Zyablitseva, “Effects of emotionally significant stimuli on behavior and respiration in rabbits with different levels of movement activity in the open field test,” Zh. Vyssh. Nerv. Deyat., 56, No. 1, 64–73 (2006).Google Scholar
  11. 11.
    U. V. Rusinova and G. Ya. Roshchina, “Interactions of the electrical activity of the sensorimotor cortex and hippocampus in ‘animal hypnosis’ in rabbits,” Zh. Vyssh. Nerv. Deyat., 50, No. 4, 600–607 (2000).Google Scholar
  12. 12.
    P. V. Simonov, The Motivated Brain [in Russian], Nauka, Moscow (1987).Google Scholar
  13. 13.
    B. H. Bland, M. G. Seto, and C. I. Rowntree, “The relation of multiple hippocampal theta cell discharge rates to slow wave theta frequency,” Physiol. Behav., 31, No. 1, 111–117 (1983).PubMedCrossRefGoogle Scholar
  14. 14.
    G. Buszaki and J. J. Chrobak, “Temporal structure in spatially organized neuronal ensembles: a role for interneuronal networks,” Curr. Opin. Neurobiol., 5, No. 4, 504–510 (1995).CrossRefGoogle Scholar
  15. 15.
    G. Carli, F. Farabollini, G. Fontani, and F. Grazzi, “Physiological characteristics of pressure immobility. Effects of morphine, naloxone and pain,” Behav. Brain Res., 12, No. 1, 55–63 (1984).PubMedCrossRefGoogle Scholar
  16. 16.
    R. J. Davidson, “Asymmetric brain function, affective style and psychopathology,” in: The Role of Early Experience and Plasticity; Devl. Psychopathol., 6, 741–758 (1994).Google Scholar
  17. 17.
    G. Fontani and G. Carli, “Hippocampal electrical activity and behavior in the rabbit,” Arch. Ital. Biol., 135, No. 1, 49–71 (1997).PubMedGoogle Scholar
  18. 18.
    H. J. Gould, “Body surface maps in the somatosensory cortex of rabbits,” J. Comp. Neurol., 243, No. 2, 207–233 (1986).PubMedCrossRefGoogle Scholar
  19. 19.
    T. Hisamitsu, M. Fujishita, S. Asamoto, A. Nakamura, and C. Takeshige, “Serotonergic neurons in the brainstem modulate animal hypnosis,” Brain Res. Bull., 29, No. 2, 141–145 (1992).PubMedCrossRefGoogle Scholar
  20. 20.
    S. Hogg, D. J. Sanger, and P. C. Moser, “Mild traumatic lesion of the right parietal cortex in the rat: characterisation of a conditioned freezing deficit and its reversal by dizocilpine,” Behav. Brain Res., 93, No. 1–2, 157–165 (1998).PubMedCrossRefGoogle Scholar
  21. 21.
    W. R. Klemm, “EEG and multiple-unit activity in limbic and motor systems during movement and immobility,” Physiol. Behav., 7, No. 3, 337–343 (1971).PubMedCrossRefGoogle Scholar
  22. 22.
    P. Konig, A. K. Engel, and W. Singer, “Relation between oscillatory activity and long-range synchronization in cat visual cortex,” Proc. Natl. Acad. Sci. USA, 92, No. 1, 290–294 (1995).PubMedCrossRefGoogle Scholar
  23. 23.
    K. A. McNish, J. C. Gewirtz, and M. Davis, “Evidence of contextual fear after lesions of the hippocampus: a distribution of freezing but not fear-potentiated startle,” J. Neurosci., 17, No. 23, 9353–9360 (1997).PubMedGoogle Scholar
  24. 24.
    S. D. Oddie and B. H. Bland, “Hippocampal formation theta activity and movement selection,” Neurosci. Biobehav. Rev., 22, No. 2, 223–231 (1998).CrossRefGoogle Scholar
  25. 25.
    B. Sacchetti, C. A. Lorenzini, E. Baldi, C. Bucherelli, M. Roberto, G. Tassoni, and M. Brunelli, “Long-lasting hippocampal potentiation and contextual memory consolidation,” Eur. J. Neurosci., 13, No. 12, 2291–2298 (2001).PubMedCrossRefGoogle Scholar
  26. 26.
    R. S. Sainsbury, A. Heynen, and C. P. Montoya, “Behavioral correlates of hippocampal type 2 theta in the rat,” Physiol. Behav., 39, No. 4, 513–519 (1987).PubMedCrossRefGoogle Scholar
  27. 27.
    S. Shimai and Y. Ohki, “Facilitation of discriminated rearing-avoidance in rats with hippocampal lesions,” Percept. Mot. Skills, 50, No. 1, 56–58 (1980).PubMedGoogle Scholar
  28. 28.
    R. K. Snider, J. F. Kabara, B. P. Roig, and A. B. Bonds, “Burst firing and modulation of functional connectivity in cat striate cortex,” J. Neurophysiol., 80, No. 2, 730–744 (1998).PubMedGoogle Scholar
  29. 29.
    H. van Lier, A. M. Coenen, and W. H. Drinkenburg, “Behavioral transitions modulate hippocampal electroencephalogram correlates of open field behavior in the rat: support for a sensorimotor function of hippocampal rhythmical synchronous activity,” J. Neurosci., 23, No. 6, 2459–2465 (2003).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2008

Authors and Affiliations

  1. 1.Institute of Higher Nervous Activity and NeurophysiologyRussian Academy of SciencesMoscowRussia

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