Effect of diblock copolymer properties on the photophysical properties of dendrimer silicon phthalocyanine nanoconjugates
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1–2 generation poly(benzyl aryl ether) dendrimer silicon phthalocyanines with axially disubstituted cyano terminal functionalities (G n -DSiPc(CN)4n , (G n = n-generation dendrimer, n = 1–2)) were synthesized. Their structures were characterized by elemental analysis, IR, 1H NMR, and ESI-MS. Polymeric nanoparticles (G n -DSiPc(CN)4n /m) were formed through encapsulating G n -DSiPc(CN)4n into three monomethoxyl poly(ethylene glycol)-poly(ε-caprolactone) diblock copolymers (MPEG–PCL) with different hydrophilic/hydrophobic proportion, respectively. The effect of dendritic generation and the hydrophilic/hydrophobic proportion of diblock copolymers on the UV/Vis and fluorescence spectra of G n -DSiPc(CN)4n and G n -DSiPc(CN)4n /m were studied. The photophysical properties of polymeric nanoparticles exhibited dendritic generation and hydrophilic/hydrophobic proportion dependence. The fluorescence intensities and lifetimes of G n -DSiPc(CN)4n /m were lower than the corresponding free dendrimer phthalocyanines. G n -DSiPc(CN)4n encapsulated into MPEG–PCL with hydrophilic/hydrophobic molecular weight ratio 2000:4000 exhibited excellent photophysical property. The mean diameter of MPEG2000–PCL2000 micelles was about 70 nm, which decreased when loaded with G n -DSiPc(CN)4n .
KeywordsPoly(ethylene glycol)-poly(ε-caprolactone) Photophysical properties Phthalocyanine Dendrimer Polymeric nanoparticles Optoelectronic applications
This research was supported by the National Key Basic Research Program of China (973 project) (2015CB352006), National Natural Science Foundation of China (61335011, 21274021), Natural Science Foundation of Fujian (2015J01040, 2015Y050), and Fujian Province Educational Project (JA15124). The projection of excellent young doctor training plan in Fujian Provincial Health System (No. 2013-ZQN-ZD-2) and Science and Technology Planning Project of Fuzhou City (2014-S-137-2).
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