Journal of Nanoparticle Research

, 14:1136

Preparation of hydrosol suspensions of elemental and core–shell nanoparticles by co-deposition with water vapour from the gas-phase in ultra-high vacuum conditions

  • Chris Binns
  • Pilar Prieto
  • Stephen Baker
  • Paul Howes
  • Ruggero Dondi
  • Glenn Burley
  • Leonardo Lari
  • Roland Kröger
  • Andrew Pratt
  • Sitki Aktas
  • John K. Mellon
Research Paper
  • 577 Downloads
Part of the following topical collections:
  1. Nanomaterials in energy, health and environment

Abstract

We report a new method to produce liquid suspensions of nanoparticles by co-deposition with water vapour from the gas-phase in ultra-high vacuum (UHV) conditions. The water is injected from outside the vacuum as a molecular beam onto a substrate maintained at 77 K and forms an ice layer with a UHV vapour pressure. Molecular dynamics simulations confirm that the nanoparticles are soft-landed close to the surface of the growing ice layer. We show that the un-agglomerated size distribution within the liquid is similar to the gas-phase size distribution and demonstrate that the inclusion of surfactants in the injected water prevents agglomeration. The method allows the flexibility and tight size control available with gas-phase production methods to be applied to making nanoparticle suspensions with any desired properties. This is important for practical applications, especially in medicine. We have extended the method to include core–shell nanoparticles, in which there is flexible control over the core size and shell thickness and free choice of the material in either. Here, we report the production of suspensions of Cu, Ag and Au elemental nanoparticles and Fe@Au and Fe@Fe-oxide core–shell nanoparticles with diameters in the range 5–15 nm. We demonstrate the power of the method in practical applications in the case of Fe@Fe-oxide nanoparticles, which have a specific absorption rate of an applied oscillating magnetic field that is significantly higher than available Fe-oxide nanoparticle suspensions and the highest yet reported. These will thus have a very high-performance in the treatment of tumours by magnetic nanoparticle hyperthermia.

Keywords

Magnetic nanoparticle hyperthermia Gas phase synthesis Core–shell nanoparticles 

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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Chris Binns
    • 1
  • Pilar Prieto
    • 2
  • Stephen Baker
    • 1
  • Paul Howes
    • 1
  • Ruggero Dondi
    • 3
  • Glenn Burley
    • 4
  • Leonardo Lari
    • 5
    • 6
  • Roland Kröger
    • 5
  • Andrew Pratt
    • 5
  • Sitki Aktas
    • 1
  • John K. Mellon
    • 7
  1. 1.Department of Physics and AstronomyUniversity of LeicesterLeicesterUK
  2. 2.Departamento de Fısica Aplicada C-XIIUniversidad Autonoma de MadridMadridSpain
  3. 3.Department of ChemistryUniversity of LeicesterLeicesterUK
  4. 4.Department of Pure and Applied ChemistryUniversity of StrathclydeGlasgowUK
  5. 5.Department of PhysicsUniversity of YorkYorkUK
  6. 6.The York JEOL Nanocentre, York Science ParkYorkUK
  7. 7.Department of Cancer Studies and Molecular MedicineUniversity of LeicesterLeicesterUK

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