Journal of Nanoparticle Research

, Volume 12, Issue 4, pp 1101–1106 | Cite as

Design and fabrication of non-superparamagnetic high moment magnetic nanoparticles for bioapplications

  • Punnapob Punnakitikashem
  • Shih-Hsin Chang
  • Chien-Wen Huang
  • J. Ping Liu
  • Yaowu Hao
Brief Communication


We present a new type of magnetic nanoparticles for bioapplications. Multilayered nanodisks consisting of two magnetic layers separated by a non-magnetic layer with two capping layers were designed and fabricated. Two key magnetic requirements for bioapplications, a high saturation magnetic moment and a near-zero remanence, were achieved through the magnetostatic interlayer coupling between two magnetic layers. Capping layers provide functionalization sites for biomolecule attachment. A pillar-template-based synthesis method was employed for fabrication. Nanodisks with a diameter of 70 nm and a thickness of 60 nm were produced in large quantity. The magnetic characterization shows that each nanodisk possesses a magnetic moment equivalent to 100 10-nm Co nanoparticles and a near-zero remanent moment.


Magnetic nanoparticles Nanodisks Pillar-template-based synthesis Drug delivery Nanomedicine 



This work was supported by the Research Enhancement Program at University of Texas at Arlington (UTA) and UTA-SPRING Joint Institutional Seed Research Program.


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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Punnapob Punnakitikashem
    • 1
  • Shih-Hsin Chang
    • 1
  • Chien-Wen Huang
    • 1
  • J. Ping Liu
    • 2
  • Yaowu Hao
    • 1
  1. 1.Department of Materials Science and EngineeringUniversity of Texas at ArlingtonArlingtonUSA
  2. 2.Department of PhysicsUniversity of Texas at ArlingtonArlingtonUSA

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