, Volume 183, Issue 3, pp 619–622 | Cite as

Liposomal Amphotericin B as Monotherapy in Relapsed Coccidioidal Meningitis

  • Ethan R. Stewart
  • Matthew L. Eldridge
  • Ian McHardy
  • Stuart H. Cohen
  • George R. ThompsonIII
Short Communication


Coccidioidal meningitis remains a difficult clinical problem, and despite life-long therapy with triazole antifungals, relapses of disease and medication intolerance occur necessitating salvage treatment. We report two patients with recurrent coccidioidal meningitis who improved following a 2-week course of liposomal amphotericin B monotherapy and discuss potential advantages of this treatment option.


Coccidioides Coccidioidomycosis Liposomal amphotericin B Meningitis Relapse 



Departmental funds were used for this project.

Compliance with Ethical Standards

Conflict of interest



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Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  • Ethan R. Stewart
    • 1
  • Matthew L. Eldridge
    • 1
  • Ian McHardy
    • 2
  • Stuart H. Cohen
    • 1
  • George R. ThompsonIII
    • 1
    • 2
  1. 1.Department of Internal Medicine, Division of Infectious DiseasesUniversity of California Davis Medical CenterSacramentoUSA
  2. 2.Department of Medical Microbiology and Immunology, Department of Medicine, Division of Infectious DiseasesUniversity of California – DavisDavisUSA

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