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Mycopathologia

, Volume 182, Issue 3–4, pp 387–392 | Cite as

Primary Cutaneous Mucormycosis Caused by Rhizopus oryzae: A Case Report and Review of Literature

  • Erika Rodríguez-Lobato
  • Lourdes Ramírez-Hobak
  • Jorge E. Aquino-Matus
  • Juan P. Ramírez-Hinojosa
  • Víctor H. Lozano-Fernández
  • Juan Xicohtencatl-Cortes
  • Rigoberto Hernández-Castro
  • Roberto Arenas
Article

Abstract

Mucormycosis is an invasive infection caused by opportunistic fungi. Rhizopus, Lichtheimia, Mucor and Rhizomucor are the most common isolated genera. Primary cutaneous mucormycosis is usually related to traumatic injuries, but immunocompromised cases are associated with underlying conditions such as diabetes mellitus and malignancies. The treatment of choice is surgical debridement and liposomal amphotericin B. We present a 40-year-old male with fever and a painful necrotic lesion on the middle back and history of poorly controlled diabetes mellitus. Rhizopus oryzae was isolated and identified using an internal transcribed spacer regions ITS1 and ITS2. An initial good response to treatment was observed; however, 7 days later a diabetic ketoacidosis due to poor adherence to treatment caused a lethal outcome.

Keywords

Primary cutaneous mucormycosis Opportunistic fungal infection Rhizopus oryzae 

Notes

Acknowledgements

We thank Cecilia González de Cossio and María Fernanda Ortega-Springall for her excellent medical assistance.

Compliance with Ethical Standards

Conflict of interest

All authors declare to have no conflict of interest.

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Copyright information

© Springer Science+Business Media Dordrecht 2016

Authors and Affiliations

  • Erika Rodríguez-Lobato
    • 1
  • Lourdes Ramírez-Hobak
    • 1
  • Jorge E. Aquino-Matus
    • 2
  • Juan P. Ramírez-Hinojosa
    • 3
  • Víctor H. Lozano-Fernández
    • 3
  • Juan Xicohtencatl-Cortes
    • 4
  • Rigoberto Hernández-Castro
    • 5
  • Roberto Arenas
    • 6
  1. 1.Servicio de DermatologíaHospital General Dr. Manuel Gea GonzálezTlalpanMexico
  2. 2.Departamento Medicina InternaHospital General Dr. Manuel Gea GonzálezTlalpanMexico
  3. 3.Departamento de InfectologíaHospital General Dr. Manuel Gea GonzálezTlalpanMexico
  4. 4.Laboratorio de Bacteriología IntestinalHospital Infantil de México Dr. Federico GómezCuauhtémocMexico
  5. 5.Departamento de Ecología de Agentes PatógenosHospital General Dr. Manuel Gea GonzálezTlalpanMexico
  6. 6.Sección de MicologíaHospital General Dr. Manuel Gea GonzálezTlalpanMexico

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