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Mycopathologia

, Volume 181, Issue 1–2, pp 97–105 | Cite as

Clinical and Laboratory Features of Six Cases of Candida and Dermatophyte Folliculitis and a Review of Published Studies

  • Murat Durdu
  • Mümtaz Güran
  • Hazal Kandemir
  • Macit Ilkit
  • Seyedmojtaba Seyedmousavi
Article
  • 344 Downloads

Abstract

Although some studies have investigated the epidemiological characteristics of Malassezia folliculitis (MF), little is known about the clinical features and laboratory characteristics of folliculitis caused by other fungi. In this prospective study, 158 patients with folliculitis were identified, and cytological and mycological examinations were performed. The positive fungal cultures were confirmed using conventional methods, ITS sequencing and HWP1 analysis. Additionally, an in vitro antifungal susceptibility test was performed. Of 158 patients with folliculitis, 65 (41.1 %) were found to have fungal folliculitis. The most common (90.8 %) fungal folliculitis was MF. Non-MF fungal folliculitis was detected in 6 (9.2 %) patients. Four patients were diagnosed with dermatophytic folliculitis (Trichophyton rubrum in three patients and Arthroderma vanbreuseghemii in one patient), and two patients were diagnosed with Candida albicans folliculitis. Although only 5 of the 6 samples were found to be positive via a potassium hydroxide test, all May–Grünwald–Giemsa-stained samples were positive. Both of the C. albicans isolates demonstrated a susceptibility profile to itraconazole, and all four dermatophytes were susceptible to terbinafine. All six patients completely recovered with systemic and topical treatment. This study revealed that dermatophytes and C. albicans are the primary causative agents of non-Malassezia fungal folliculitis. We compared our findings with published reports on fungal folliculitis.

Keywords

Fungal folliculitis Candida folliculitis Dermatophytic folliculitis Acantholytic cell Cytology 

Notes

Acknowledgments

This publication was prepared as a collaborative study between the Department of Dermatology, Faculty of Medicine, Başkent University Adana Hospital, Adana, Turkey, the Division of Mycology, Department of Microbiology, Faculty of Medicine, University of Çukurova, Adana, Turkey, and the Department of Medical Microbiology, Radboud UMC, Nijmegen, the Netherlands.

Funding

This study was supported in part by the Department of Dermatology, Faculty of Medicine, Başkent University Adana Hospital, Adana, Turkey, and the Department of Medical Microbiology, Radboud UMC, Nijmegen, the Netherlands.

Compliance with Ethical Standards

Conflict of interest

None.

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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  • Murat Durdu
    • 1
  • Mümtaz Güran
    • 2
    • 3
  • Hazal Kandemir
    • 2
  • Macit Ilkit
    • 2
  • Seyedmojtaba Seyedmousavi
    • 4
    • 5
    • 6
  1. 1.Department of Dermatology, Faculty of MedicineBaşkent University Adana HospitalAdanaTurkey
  2. 2.Division of Mycology, Department of Microbiology, Faculty of MedicineUniversity of ÇukurovaAdanaTurkey
  3. 3.Department of Microbiology, Faculty of MedicineEastern Mediterranean UniversityFamagusta, Cyprus, Mersin 10Turkey
  4. 4.Department of Medical MicrobiologyRadboud UMCNijmegenThe Netherlands
  5. 5.Department of Medical Microbiology and Infectious DiseasesErasmus MCRotterdamThe Netherlands
  6. 6.Invasive Fungi Research CenterMazandaran University of Medical SciencesSariIran

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