, Volume 169, Issue 5, pp 381–386 | Cite as

Chromoblastomycosis in Sub-Tropical Regions of India

  • Ajanta Sharma
  • Naba K. Hazarika
  • Deepak Gupta


Chromoblastomycosis is a chronic fungal infection caused by several pigmented fungi commonly seen in tropical and sub-tropical climate. We report here two cases of chromoblastomycosis from the tea gardens of Assam, a state in the north-eastern region of India having a subtropical climate. Of the two patients, one presented with extensive lesions covering a large area of the body and gave a past history of thorn prick in his right foot. The laboratory diagnosis was done by direct microscopy and culture of skin scraping and biopsy tissue and the isolate was identified as Cladophialophora carrionii. On contrary to the fact that Chromoblastomycosis is known for its slow spread and chronic nature, a rapid spread of the disease within a short span of 8 months was noticed in this case affecting the livelihood of the patient. To best of our knowledge, this is the first report of chromoblastomycosis caused by Cladophialophora carrionii from Assam. In the second patient, a large cauliflower like mass in the leg was the presenting feature. Diagnosis was confirmed by microscopy and culture of the biopsy tissue. Fonsecaea pedrosoi was isolated from this case. Both the patients were treated with Fluconazole and showed slight improvement with decrease in size of the lesions after 1 month.


Chromoblastomycosis Sclerotic body Fonsecaea pedrosoi Cladophialophora carrionii Assam 


  1. 1.
    Esterre P. Chromoblastomycosis. In: Merz WG, Hay RJ, editors. Topley and Wilson’s microbiology and microbial infection (medical mycology). London: Hodder Arnold Publication; 2005. p. 356–66.Google Scholar
  2. 2.
    Rudolph M. Uber die brasilianische (Figueira). Arch Schiffs Tropen-Hygiene. 1914;18:498.Google Scholar
  3. 3.
    Emmons CW, Binford CH, Utz JP, Kwon-Chung KJ. Chromomycosis. In: Emmons CW, Binford CH, Utz JP, Kwon-Chung KJ, editors. Medical mycology. London: Henry Kimpton Publishers; 1977. p. 386–405.Google Scholar
  4. 4.
    Kobayashi GS, Pappagianis D. The mycosis. In: Sonnenwirth AC, Jarett L, editors. Gradwohl’s clinical laboratory methods and diagnosis. New Delhi: Jarett L.B.I. Publication Ltd; 1990. p. 2211–39.Google Scholar
  5. 5.
    Fuentes CA, Bosch ZE. Biochemical differentiation of the etiologic agents of chromoblastomycosis from non-pathogenic Cladosporium species. J Invest Dermatol. 1960;34:419–21.PubMedGoogle Scholar
  6. 6.
    Henry L, Ross AP. Chromoblastomycosis (possibly Cladosporium) of the breast in an English woman. J Clin Pathol. 1967;20:124–7.CrossRefPubMedGoogle Scholar
  7. 7.
    Pradhan SV, Talwar OP, Ghosh A, Ravi MS, Shiva Raj KC, Gupta S. Chromoblastmycosis in Nepal: a study of 13 cases. IJDVL. 2007;73:176–8.Google Scholar
  8. 8.
    Kakoti LM, Dey NC. Chromoblastomycosis in India. J Ind Med Assoc. 1957;28:351–5.Google Scholar
  9. 9.
    Rasul ES, Hazarika NK, Sharma A, Barua PC, Sen SS. Chromoblastomycosis. JAPI. 2007;55:149–51.PubMedGoogle Scholar
  10. 10.
    Rajendran C, Ramesh V, Misra RS, Kandhari S, Upreti HB, Datta KK. Chromoblastomycosis in India. Int J Dermatol. 1997;36:29–33.CrossRefPubMedGoogle Scholar
  11. 11.
    Sharma NL, Sharma RC, Grover PS, Gupta ML, Sharma AK, Mahajan Vk. Chromoblastomycosis in India. Int J Dermatol. 1999;38:846–51.CrossRefPubMedGoogle Scholar
  12. 12.
    Queiroz-Teller F, McGinnis MR, Salkin I, Graybill JR. Subcutaneous mycoses. Infect Dis Clin North Am. 2003;17:59–85.CrossRefGoogle Scholar
  13. 13.
    Mohanty L, Mohanty P, Padhi T, Samantray S. Verrucous growth on leg. IJDVL. 2006;72(5):399–400.Google Scholar
  14. 14.
    Mary J, Prasad PVS, Bhaktaviziam A. Chromoblastomycosis with squamous cell carcinoma. IJDVL. 1988;54:314–7.Google Scholar
  15. 15.
    Gezuele E, Mackinnon JE, Conti-Diaz IA. The frequent isolation of Phialophora verrucosa from natural source. Sabouraudia. 1972;10:266–73.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Ajanta Sharma
    • 1
  • Naba K. Hazarika
    • 1
  • Deepak Gupta
    • 1
  1. 1.Gauhati Medical CollegeGuwahatiIndia

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