An efficient computerized decision support system for the analysis and 3D visualization of brain tumor

Abstract

The quality of health services provided by medical centers varies widely, and there is often a large gap between the optimal standard of services when judged based on the locality of patients (rural or urban environments). This quality gap can have serious health consequences and major implications for patient’s timely and correct treatment. These deficiencies can manifest, for example, as a lack of quality services, misdiagnosis, medication errors, and unavailability of trained professionals. In medical imaging, MRI analysis assists radiologists and surgeons in developing patient treatment plans. Accurate segmentation of anomalous tissues and its correct 3D visualization plays an important role inappropriate treatment. In this context, we aim to develop an intelligent computer-aided diagnostic system focusing on human brain MRI analysis. We present brain tumor detection, segmentation, and its 3D visualization system, providing quality clinical services, regardless of geographical location, and level of expertise of medical specialists. In this research, brain magnetic resonance (MR) images are segmented using a semi-automatic and adaptive threshold selection method. After segmentation, the tumor is classified into malignant and benign based on a bag of words (BoW) driven robust support vector machine (SVM) classification model. The BoW feature extraction method is further amplified via speeded up robust features (SURF) incorporating its procedure of interest point selection. Finally, 3D visualization of the brain and tumor is achieved using volume marching cube algorithm which is used for rendering medical data. The effectiveness of the proposed system is verified over a dataset collected from 30 patients and achieved 99% accuracy. A subjective comparative analysis is also carried out between the proposed method and two state-of-the-art tools ITK-SNAP and 3D-Doctor. Experimental results indicate that the proposed system performed better than existing systems and assists radiologist determining the size, shape, and location of the tumor in the human brain.

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Notes

  1. 1.

    https://figshare.com/articles/BRATS_2013_Leaderboard_and_Test_Datasets/1348692

  2. 2.

    http://www.vtk.org/

  3. 3.

    http://www.lrh.gov.pk/

  4. 4.

    http://www.itksnap.org/pmwiki/pmwiki.php

  5. 5.

    http://www.ablesw.com/3d-doctor/?

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Acknowledgments

This research was supported by the Korean MSIT (Ministry of Science and ICT), under the National Program for Excellence in SW (2015-0-00938), supervised by the IITP (Institute for Information & communications Technology Promotion).

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Correspondence to Muhammad Sajjad.

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Mehmood, I., Sajjad, M., Muhammad, K. et al. An efficient computerized decision support system for the analysis and 3D visualization of brain tumor. Multimed Tools Appl 78, 12723–12748 (2019). https://doi.org/10.1007/s11042-018-6027-0

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Keywords

  • Medical image processing
  • Tumor segmentation and classification
  • MRI images
  • Medical imaging
  • MRI 3D visualization