Regulation mechanism of microRNA in plant response to abiotic stress and breeding

Abstract

microRNAs (miRNAs) in plants are a class of small RNAs consisting of approximately 21–24 nucleotides. The mature miRNA binds to the target mRNA through the formation of a miRNA-induced silencing complex (MIRISC), and cleaves or inhibits translation, thereby achieving negative regulation of the target gene. Based on miRNA plays an important role in regulating plant gene expression, studies on the prediction, identification, function and evolution of plant miRNAs have been carried out. In addition, many researches prove that miRNAs are also involved in many kinds of abiotic and biotic stress, under abiotic stress, plants can express some miRNA, and act on stress-related target genes, which can make plants adapt to stress in physiological response. In this review, the synthetic pathway and mechanism of plant miRNA are briefly described, and we discuss the biological functions and regulatory mechanisms of miRNAs responding to abiotic stresses including low temperature, salt, drought stress and breeding to lay the foundation for further exploring the mechanism of action of miRNAs in stress resistance of plant. And analyze its utilization prospects in plant stress resistance research.

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Fig. 1
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(Reproduced with permission from Sun et al. [92])

Fig. 4

(Reproduced with permission from Ding et al. [114])

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Acknowledgements

We are grateful for financial support from Shandong Provincial Natural Science Foundation (ZR2016JL028), Major Program of Shandong Provincial Natural Science Foundation (2017C03), Shandong Provincial Natural Science Foundation (ZR2015EM007).

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XS wrote the manuscript. NS and LL modified the article. All authors read and approved the final manuscript.

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Correspondence to Na Sui.

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Sun, X., Lin, L. & Sui, N. Regulation mechanism of microRNA in plant response to abiotic stress and breeding. Mol Biol Rep 46, 1447–1457 (2019). https://doi.org/10.1007/s11033-018-4511-2

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Keywords

  • microRNA
  • Function
  • Plant
  • Abiotic stress