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Molecular Biology Reports

, Volume 38, Issue 8, pp 5397–5403 | Cite as

Genetic data of 15 autosomal STR loci: an analysis of the Araraquara population colonization (São Paulo, Brazil)

  • Joyce Aparecida Martins
  • Raquel de Freitas Figueiredo
  • Cyntia Sumie Yoshizaki
  • Greiciane Gaburro Paneto
  • Regina Maria Barretto Cicarelli
Article

Abstract

The genetic markers most commonly utilized to determine identity and in paternity testing are autosomal short tandem repeats (STRs); to interpret the DNA analysis, the results of a case have to be compared with a pertinent reference population. Thus, the aim of this work was to characterize the genetic profile of the population of Araraquara (São Paulo, Brazil) by analyzing 15 STR loci included in the PowerPlex® 16 System and to correlate these data with the migration history of the population. No deviations from the Hardy–Weinberg equilibrium were observed for any of the loci, after Bonferroni’s correction. Forensic parameters exhibited high values, the most polymorphic loci being Penta E, D18S51 and FGA. An unweighted pair-group method with arithmetic mean (UPGMA) tree based on genetic distances showed that the current population of Araraquara is grouped with populations of the southeastern region of Brazil, which are close to the European group but distant from African and Amerindian populations. Estimates of admixture components revealed that the contributions to the population of Araraquara were 76% European, 18% African, and 6% Amerindian.

Keywords

STR Allele frequencies PowerPlex® 16 System Araraquara Brazil 

Notes

Acknowledgments

This study was partially supported by the Programa de Apoio ao Desenvolvimento Científico (PADC) of the Faculdade de Ciências Farmacêuticas da Universidade Estadual Paulista (proc. 2002/13-I) and by the Fundação para o Desenvolvimento da UNESP (FUNDUNESP, proc. 164/03). JAM was the recipient of a fellowship from the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq).

Supplementary material

11033_2011_693_MOESM1_ESM.pdf (134 kb)
Supplementary material 1 (PDF 134 kb)

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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Joyce Aparecida Martins
    • 1
  • Raquel de Freitas Figueiredo
    • 1
  • Cyntia Sumie Yoshizaki
    • 1
  • Greiciane Gaburro Paneto
    • 1
  • Regina Maria Barretto Cicarelli
    • 1
  1. 1.Laboratório de Investigação de Paternidade, Faculdade de Ciências FarmacêuticasUnesp-Univ Estadual PaulistaAraraquaraBrazil

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