Molecular Biology Reports

, Volume 38, Issue 5, pp 3401–3409 | Cite as

The complete mitochondrial genome of the hard clam Meretrix meretrix

  • Chong-bo He
  • Jian Wang
  • Xiang-gang Gao
  • Wen-tao Song
  • Hong-jun Li
  • Yun-feng Li
  • Wei-dong Liu
  • Hao Su


Veneridae is a diverse, commercially important, and cosmopolitan family. Here we present the complete mitochondrial genome of the hard clam Meretrix meretrix (Bivalvia: Veneridae). The entire mitochondrial genome (mitogenome) sequence of M. meretrix is 19,826 bp in length, and contains 37 genes including 12 protein-coding genes, 2 ribosomal RNAs, and 23 tRNAs. All genes are encoded on the heavy strand. In contrast to the typical animal mitochondrial genome, it lacks the protein-coding gene ATP8, and has only one copy of the tRNASer gene, but three duplications of the tRNAGln, which is the first report among the present molluscan mtDNAs. We observed that the gene arrangement between M. meretrix and M. petechialis is same except one more tRNAGln gene in M. meretrix., and the sequence similarity is as high as 99%, indicating that M. petechialis and M. meretrix could be treated as a junior synonym of M. meretrix. Maximum Likelihood and Bayeslan analysis of 12 concatenated protein-coding amino acid sequences place the Unionidae as a sister group to other bivalves, which reflects the general opinion that the Unionidae deverged very early in Bivalvia evolution.


Meretrix meretrix Mitochondrial genome mtDNA Bivalvia Gene arrangement Phylogenetic analysis 


Atp6 and 8

Genes encoding ATPase subunits 6 and 8


Base pairs


Genes encoding cytochrome oxidase subunits I–III

Cyt b

Gene encoding cytochrome b

ND1-6 and 4L

Genes encoding NADH dehydrogenase subunits 1–6 and 4L

lrRNA and srRNA

Large (16S) and small (12S) ribosomal RNA subunit (gene)


Transfer RNA








Non-coding region



This work was supported by National Nature Science Foundation of China (No.:30972246), Liaoning Key Project of Sci-Tech (No.: 2008203001) and Liaoning scientific research program of ocean and fisheries department (No.:200801). We give thanks to the two anonymous reviewers who provided constructive comments that significantly improved the manuscript.

Supplementary material

11033_2010_449_MOESM1_ESM.docx (379 kb)
Supplementary material 1 (DOCX 379 kb)


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Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Chong-bo He
    • 1
  • Jian Wang
    • 1
    • 2
  • Xiang-gang Gao
    • 1
  • Wen-tao Song
    • 1
    • 3
  • Hong-jun Li
    • 1
  • Yun-feng Li
    • 1
  • Wei-dong Liu
    • 1
  • Hao Su
    • 1
  1. 1.The Key Laboratory of Marine Fishery Molecular Biology of Liaoning ProvinceLiaoning Ocean and Fisheries Science Research InstituteDalianChina
  2. 2.College of Life ScienceLiaoning Normal UniversityDalianChina
  3. 3.College of Life ScienceShanghai Ocean UniversityShanghaiChina

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