Molecular Biology Reports

, Volume 37, Issue 1, pp 333–337 | Cite as

Population genetic study of four closely-linked X-STR trios in Koreans

  • Jeong Eun Sim
  • Hwan Young Lee
  • Woo Ick Yang
  • Kyoung-Jin Shin


We investigated four X chromosomal short tandem repeat (X-STR) markers (DXS10079, DXS10103, DXS10146, and DXS10148) in 450 unrelated Koreans (300 males and 150 females), and evaluated their forensic usage in relation to the four X-STR linkage groups. Forensic statistical parameters for these X-STR markers indicated that they are highly informative for forensic application in Koreans. No significant deviations from Hardy-Weinberg equilibrium were observed in any of the four X-STR markers. In addition, we present haplotypes and their frequency data for four linkage groups each comprised of three X-STRs (DXS10148-DXS10135-DXS8378, DXS7132-DXS10079-DXS10074, DXS10103-HPRTB-DXS10101, and DXS10146-DXS10134-DXS7423) in 300 males. Haplotype diversity values in the four linkage trios were all higher than 0.98, and 77.1% of all haplotypes showed a frequency less than 0.01. Therefore, the four closely-linked X-STR trios will contribute to complex kinship testing in Koreans.


X-STR DXS10079 DXS10103 DXS10146 DXS10148 Koreans 



This work was supported by the Korea Science and Engineering Foundation (KOSEF) grant funded by the Korean government (MEST) (No. M10640030002-08N4003-00210).

Supplementary material

11033_2009_9733_MOESM1_ESM.pdf (123 kb)
Supplementary material (PDF 122 kb). Table S1 Haplotype frequencies of four closely-linked X-STR trios in a Korean population


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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Jeong Eun Sim
    • 1
  • Hwan Young Lee
    • 1
    • 2
  • Woo Ick Yang
    • 1
  • Kyoung-Jin Shin
    • 1
    • 2
  1. 1.Department of Forensic Medicine and Brain Korea 21 Project for Medical ScienceYonsei University College of MedicineSeoulKorea
  2. 2.Human Identification Research CenterYonsei UniversitySeoulKorea

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