Associated analysis of single nucleotide polymorphisms of IGF2 gene’s exon 8 with growth traits in Wuzhishan pig
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A new SNP located in IGF-2 gene of Wuzhishan pig was detected while a C → T silent mutation at position 17 of exon 8 was detected by Single-Strand Conformational Polymorphism (SSCP). The value of polymorphism information content (PIC) indicated that this locus had intermediate polymorphism information content (0.25 < PIC < 0.5). The results of the fitness of Hardy-Weinberg equilibrium was in disequilibrium (P < 0.01). SAS analysis together with the multiple comparisons between polymorphisms and growth traits showed that: the differences of carcass weight (P = 0.024), withers height (P = 0.037) and chest girth (P = 0.025) in 10-month-old generation group were very remarkable.
KeywordsWuzhishan pig IGF2 gene Single nucleotide polymorphisms Growth traits Correlation analysis
This experiment was supported by National Nonprofit Institute Research Grant of CATAS-TCGRI (grant PZS-013) and Communion Platform Constructional Project for Livestock & Poultry Germplasm Resource (grant 2005DKA21101) as well.
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