Molecular Diversity

, Volume 22, Issue 3, pp 743–749 | Cite as

Microwave-assisted green synthesis of 4,5-dihydro-1H-pyrazole-1-carbothioamides in water

  • Hamid Reza Farmani
  • Mohammad Hossein Mosslemin
  • Bahareh Sadeghi
Short Communication


Rapid, efficient, simple and green procedure for the synthesis of 4,5-dihydro-1H-pyrazole-1-carbothioamides via the multicomponent reaction of aryl aldehydes, acetophenones and thiosemicarbazide in water in the presence of tetrabutylammonium hydroxide under microwave irradiation is reported.


4,5-Dihydro-1H-pyrazole-1-carbothioamides Microwave irradiation Multicomponent reaction Green chemistry Water TBAOH MCRs 

Supplementary material

11030_2018_9814_MOESM1_ESM.docx (16.7 mb)
Supplementary material 1 (docx 17147 KB)


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Hamid Reza Farmani
    • 1
  • Mohammad Hossein Mosslemin
    • 1
  • Bahareh Sadeghi
    • 1
  1. 1.Department of Chemistry, Yazd BranchIslamic Azad UniversityYazdIran

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