Molecular Diversity

, Volume 20, Issue 1, pp 111–152 | Cite as

The molecular diversity scope of 1,3-indandione in organic synthesis

  • Shima Asadi
  • Ghodsi Mohammadi Ziarani
Comprehensive review


Indandione is an important starting material that has drawn great attention in various organic transformations because of its attributes, such as low cost, easy to handle and eco-friendliness generally affording the corresponding products in excellent yields. In this review, we summarize recent data describing the most important MCRs reactions in which one of the starting materials is indandione. This review will also present two-, three-, four-, and five-component and one-pot reactions for the functionalization of indandione with the to increase awareness on the versatility of using this compound among organic chemists.


Indandione Organic synthesis  Multicomponent reaction MCRs Cylcization  Functionalization 



We gratefully acknowledge the financial support from the Research Council of Alzahra University.


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© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.Department of Chemistry, School of SciencesAlzahra UniversityTehranIran

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