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Fe(ClO4)3· 6H2O: a mild and efficient catalyst for one-pot three component synthesis of β-acetamido carbonyl compounds under solvent-free conditions

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Abstract

A one-pot multi-component reaction for the synthesis of β-acetamido carbonyl compounds is reported. The reaction uses a variety of aldehydes, acetophenone derivatives or methyl acetoacetate, acetonitrile, and acetyl chloride in the presence of ferric perchlorate, a mild, efficient and inexpensive catalyst effective under solvent free conditions.

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Authors and Affiliations

  1. Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran

    Majid M. Heravi, Farahnaz K. Behbahani, Mansoureh Daraie & Hossein A. Oskooie

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  1. Majid M. Heravi
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  2. Farahnaz K. Behbahani
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  3. Mansoureh Daraie
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  4. Hossein A. Oskooie
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Correspondence to Majid M. Heravi.

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Heravi, M.M., Behbahani, F.K., Daraie, M. et al. Fe(ClO4)3· 6H2O: a mild and efficient catalyst for one-pot three component synthesis of β-acetamido carbonyl compounds under solvent-free conditions. Mol Divers 13, 375–378 (2009). https://doi.org/10.1007/s11030-009-9118-z

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  • DOI: https://doi.org/10.1007/s11030-009-9118-z

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