Molecular Diversity

, 12:197 | Cite as

A novel method for the synthesis of substituted 3,4-dihydrocoumarin derivatives via isocyanide-based three-component reaction

  • Ahmad Shaabani
  • Afshin Sarvary
  • Ebrahim Soleimani
  • Ali Hossein Rezayan
  • Marjan Heidary
Short Communication


A new one-pot procedure for the efficient synthesis of novel 3,4-dihydrocoumarin derivatives using commercially available substituted 2-hydroxybenzaldehydes, Meldrum’s acid, and isocyanides by a three-component condensation reaction in dichloromethane at room temperature without using any catalysts and activation was developed.


Isocyanide 3,4-Dihydrocoumarin derivatives Multi-component reactions 2-Hydroxybenzaldehydes 


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Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  • Ahmad Shaabani
    • 1
  • Afshin Sarvary
    • 1
  • Ebrahim Soleimani
    • 1
  • Ali Hossein Rezayan
    • 1
  • Marjan Heidary
    • 1
  1. 1.Department of ChemistryShahid Beheshti UniversityTehranIran

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