Journal of Thermal Analysis and Calorimetry

, Volume 120, Issue 1, pp 1043–1051 | Cite as

Study on hot property differences of Aconiti Lateralis Radix Praeparata and its compatibility with different ginger processed products based on bio-thermodynamics

  • Zhe Chen
  • Yanling Zhao
  • Shuxian Liu
  • Quanfu Zheng
  • Tiantian Liu
  • Xiao Ma
  • Ping Zhang
  • Ruisheng Li
  • Lifu Wang
  • Yonggang Li
  • Yaming Zhang
  • Xiaohe Xiao


Aconiti Lateralis Radix Praeparata (ALRP) is commonly used traditional Chinese medicine in clinic, and it is usually in compatibility with ginger including Zingiberis Rhizoma (ZR), Zingiberis Rhizoma Recens (ZRR), and Zingiberis Rhizoma Praeparatum (ZRP) for treatment of diseases. In this paper, microcalorimetry and Cold/Hot plate differentiating technology (CHPD) were employed to explore the hot property differences of ALRP, together with its compatibility with different ginger processed products. By means of principal component analysis (PCA), the heat power of the second peak (P 2) and the total heat output (Q) which were the main parameters affecting the E. coli metabolism from the power-time curves were obtained. The results showed that the hot property of ALRP in compatibility with different processed ginger was in order of ZR + ALRP > ZRR + ALRP > ZRP + ALRP > ALRP. Meanwhile, the oxygen consumption and remaining rate (RR) in mice on warm plate suggested that the hot property of ALRP was totally different. The relationships between the main parameters (P 2 and Q) values and the observation indexes from CHPD were investigated with canonical correlation analysis. The correlation coefficient showed that parameter Q had a marked correlation with the observation indexes (R > 0.85). Altogether, based on bio-thermodynamics, the hot property differences of ALRP and its compatibility with different ginger processed products followed the order of ZR + ALRP > ZRR + ALRP > ZRP + ALRP > ALRP. This could provide guidance for clinical use of ALRP combining with different ginger processed products.


Ginger processed products Aconiti Lateralis Radix Praeparata Hot property differences Bio-thermodynamics 



Aconiti Lateralis Radix Praeparata


Traditional Chinese medicine


Zingiberis Rhizoma


Zingiberis Rhizoma Recens


Zingiberis Rhizoma Praeparatum


Cold/Hot plate differentiating technology


Principal component analysis


The heat power of the second peak


The total heat output


Remaining rate on warm plate


Canonical correlation analysis



We are grateful for the support of the National Natural Sciences Foundation (No. 81173571), National Basic Research Program of China (No. 2007CB512607), and the Major Projects of the National Science and Technology (2012ZX10005010-002-002).


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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2014

Authors and Affiliations

  • Zhe Chen
    • 1
    • 2
  • Yanling Zhao
    • 2
  • Shuxian Liu
    • 1
    • 2
  • Quanfu Zheng
    • 1
    • 2
  • Tiantian Liu
    • 1
    • 2
  • Xiao Ma
    • 1
    • 2
  • Ping Zhang
    • 2
  • Ruisheng Li
    • 2
  • Lifu Wang
    • 2
  • Yonggang Li
    • 2
  • Yaming Zhang
    • 2
  • Xiaohe Xiao
    • 2
  1. 1.Pharmacy CollegeChengdu University of Traditional Chinese MedicineChengduChina
  2. 2.China Military Institute of Chinese MedicineBeijingChina

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