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Journal of Thermal Analysis and Calorimetry

, Volume 113, Issue 3, pp 1369–1377 | Cite as

Thermal stability of new biologic active copper(II) complexes with 5,6-dimethylbenzimidazole

  • Ioana Dorina Vlaicu
  • Madalina Constand
  • Rodica Olar
  • Dana Marinescu
  • Maria Nicoleta Grecu
  • Veronica Lazar
  • Mariana Carmen Chifiriuc
  • Mihaela Badea
Article

Abstract

Three new coordinative compounds that contain mixed ligands (5,6-dimethylbenzimidazole and acrylato anion) were synthesized and characterized. The features of complexes have been assigned from microanalytical, IR, UV–Vis and EPR spectra as well as thermal analysis. IR data are in accordance with unidentate nature of 5,6-dimethylbenzimidazole while the acrilato ion acts as uni- or bidentate ligand. The electronic spectra display the characteristic pattern of square pyramidal or octahedral stereochemistry, which were confirmed by the EPR spectra. Antibacterial and antifungal activities of the complexes have been determined in vitro, against various Gram-negative and Gram-positive bacteria and fungi. The tested complexes exhibited different spectra of antimicrobial activity and inhibited the microbial ability to colonize the inert surfaces, acting as potential anti-adherence and biofilm-controlling agents. Thermal decomposition evidenced several well-defined steps as dehydration (complex 2), 5,6-dimethylbenzimidazole molecule release (all complexes) and the acrylate decomposition in carbonate (complex 3). The final residue is in all cases copper (II) oxide.

Keywords

Acrylate Copper complex 5,6-dimethylbenzimidazole Thermal behaviour 

Notes

Acknowledgements

This paper was supported by the Sectorial Operational Programme Human Resources Development (SOP HRD), financed from the European Social Fund and by the Romanian Government under the contract number SOP HRD/107/1.5/S/82514.

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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2013

Authors and Affiliations

  • Ioana Dorina Vlaicu
    • 1
  • Madalina Constand
    • 1
  • Rodica Olar
    • 1
  • Dana Marinescu
    • 1
  • Maria Nicoleta Grecu
    • 2
  • Veronica Lazar
    • 3
  • Mariana Carmen Chifiriuc
    • 3
  • Mihaela Badea
    • 1
  1. 1.Department of Inorganic ChemistryFaculty of Chemistry, University of BucharestBucharestRomania
  2. 2.National Institute of Materials PhysicsMăgurele-IlfovRomania
  3. 3.Department of MicrobiologyFaculty of Biology, University of BucharestBucharestRomania

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