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Journal of Thermal Analysis and Calorimetry

, Volume 107, Issue 3, pp 1339–1344 | Cite as

Thermodynamic properties of laburnine in saline and glucose solutions

  • Z. X. Li
  • X. H. Pu
  • W. W. Zhao
Article

Abstract

Laburnine’s dissolution behaviors in glucose and saline solution were studied by a micro-calorimetry method. The measured integral and differential heats of solution were utilized to build equations of the solute and the heat, so that dissolution thermodynamic equations and half-time periods, Δsol H m, Δsol G m, and Δsol S m were obtained. The results show that this study does not only provide a simple method for the determination of the half-life period for a drug but also offer a theoretical reference for the clinical application of laburnine.

Keywords

Thermodynamics Dynamics Laburnine Saline Glucose 

Notes

Acknowledgements

This study was supported by the Phytochemistry Key Laboratory of Shaanxi Province (No. 09JS066), and the Project Foundation of Shaanxi Province (No. 2006k16-G16) in the People’s Republic of China.

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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2011

Authors and Affiliations

  1. 1.Department of Chemistry and Chemical EngineeringBaoji University of Arts and SciencesBaojiPeople’s Republic of China

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