Abstract
Heat capacity of methacetin (N-(4-methoxyphenyl)-acetamide) has been measured in the temperature range 5.8–300 K. No anomalies in the C p(T) dependence were observed. Thermodynamic functions were calculated. At 298.15 K, the values of entropy and enthalpy are equal to 243.1 J K−1 mol−1 and 36360 J mol−1, respectively. The heat capacity of methacetin in the temperature range 6–10 K is well fitted by Debye equation C p = AT 3. The thermodynamic data obtained for methacetin are compared with those for the monoclinic and orthorhombic polymorphs of paracetamol.
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Acknowledgements
The authors are grateful to Dr. T. Drebushchak for X-ray characterization of the sample. The study was supported by the Integration Project 109 of the Siberian Branch of the Russian Academy of Sciences.
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Paukov, I.E., Kovalevskaya, Y.A., Arzamastcev, A.E. et al. Heat capacity of methacetin in a temperature range of 6 to 300 K. J Therm Anal Calorim 108, 243–247 (2012). https://doi.org/10.1007/s10973-011-1505-x
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DOI: https://doi.org/10.1007/s10973-011-1505-x