Journal of Sol-Gel Science and Technology

, Volume 81, Issue 2, pp 367–371 | Cite as

Monodisperse erythrocyte-like and hollow erythrocyte-like silica nanoparticles prepared by a simple template-free and surfactant-free sol–gel route

Brief Communication: Nano-structured materials (particles, fibers, colloids, composites, etc.)


This paper introduced a simple two-step aqueous method in which monodisperse erythrocyte-like silica nanoparticles could be prepared without surfactant and template by sol–gel method. KOH was used to form the asymmetrical silica nanoparticles through quickly condensation in rotation system. The erythrocyte-like hollow silica nanoparticles with the same external contour could be obtained by further hydrothermal. In addition, double-layer hollow erythrocyte-like and cage-like structures nanoparticles could also be acquired by hydrothermal reaction. A simple and green method was found to work in a dynamic process and produce asymmetrical structure getting rid of the minimization of interfacial energy.

Graphical Abstract

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Erythrocyte-like silica nanoparticles Hollow erythrocyte-like silica nanoparticles Template-free Surfactant-free Sol–gel method Hydrothermal 



This work was supported by National Natural Science Foundation of China (Grant No. 51503006).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.School of Materials Science and Mechanical EngineeringBeijing Technology and Business UniversityBeijingPeople’s Republic of China
  2. 2.Department of Chemical Engineering, Advanced Materials LaboratoryTsinghua UniversityBeijingPeople’s Republic of China

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