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Synthesis and characterization of praseodymium-2-hydroxypropyl-β-cyclodextrin inclusion complex

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Abstract

The inclusion complex of PrCl3-XH2O-2-hidroxypropyl-β-cyclodextrin (Pr-2HPβCD) was prepared to increase the solubility and stability of PrCl3-XH2O. As techniques of characterization, UV-Vis spectroscopy, scanning electron microscopy, X-ray diffraction, infrared spectroscopy, and Raman spectroscopy were used and confirmed the inclusion complex Pr-2HPβCD’s formation. By UV-Vis spectrophotometry, three wavelength regions were established to determine praseodymium in a wide range of concentration in the presence of 2-hidroxypropyl-β-cyclodextrin (2HPβCD). When the Pr-2HPβCD inclusion complex was irradiated with gamma radiation from cobalt-60 at doses between 1 and 500 Gy, the material not changed significantly. However, when the inclusion complex was irradiated between 5000 and 10,000 Gy, small changes occurred, showing that the inclusion complex began to decompose. The Pr-2HPβCD inclusion complex formation contributes to research with new applications of the praseodymium as a therapeutic agent.

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Authors and Affiliations

  1. Dirección de Investigación Científica, Gerencia de Ciencias Básicas, Departamento de Química, Instituto Nacional de Investigaciones Nucleares, Apartado Postal 18-1027, 11801, Mexico, D. F, Mexico

    Hilario López-González, Erick Moreno-Cruz & Jaime Jiménez Becerril

  2. Departamento de Química. Área de Química Analítica, Universidad Autónoma Metropolitana-Iztapalapa, Apartado Postal 55-534, 09340, Mexico, D. F, Mexico

    Alberto Rojas-Hernández

  3. Tecnológico de Estudios Superiores de San Felipe del Progreso, Avenida Tecnológico S/N, Ejido de San Felipe del Progreso, 50640, San Felipe Del Progreso, Mexico

    Erick Moreno-Cruz

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  1. Hilario López-González
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  2. Erick Moreno-Cruz
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  3. Alberto Rojas-Hernández
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  4. Jaime Jiménez Becerril
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Correspondence to Jaime Jiménez Becerril.

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López-González, H., Moreno-Cruz, E., Rojas-Hernández, A. et al. Synthesis and characterization of praseodymium-2-hydroxypropyl-β-cyclodextrin inclusion complex. J Radioanal Nucl Chem 319, 837–845 (2019). https://doi.org/10.1007/s10967-018-6369-0

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  • DOI: https://doi.org/10.1007/s10967-018-6369-0

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