Journal of Radioanalytical and Nuclear Chemistry

, Volume 314, Issue 2, pp 1309–1317 | Cite as

Nano-titania: a novel purification and concentration adsorbent for 125I production for medical uses



The presented work describes the efficient use of nano-crystalline titania (TiO2) to remove trace levels of cesium radio-contaminants (134Cs and 137Cs) in iodine-125 (125I) solution produced via neutron activation of natural 124Xe target. The adsorption parameters of TiO2 were investigated to attain the optimum purification and concentration conditions of 125I solution. The maximum sorption capacity of Cs and 125I were approximately 56 and 67 mg/g TiO2, respectively. The final 125I solution was of high radiochemical, radionuclidic and chemical purities, besides, it showed high radioactive concentration that confirming its suitability for nuclear medicine applications and 125I brachytherapy sources preparation.

Graphical abstract


125134Cs 137Cs Nano-titania Natural xenon Neutron activation Column chromatography 


Compliance with ethical standards

Conflict of interest

All authors declares that they have no conflict of interest.


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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2017

Authors and Affiliations

  1. 1.Radioactive Isotopes and Generators Department, Hot Laboratories CentreAtomic Energy AuthorityCairoEgypt
  2. 2.Pharmaceutical Chemistry Department, Faculty of PharmacyOctober University of Modern Sciences and Arts (MSA)GizaEgypt

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