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Journal of Radioanalytical and Nuclear Chemistry

, Volume 307, Issue 3, pp 1645–1649 | Cite as

Tracking inorganic elements in GRMD blood dogs submitted to hASCs investigated by NAA technique

  • S. Metairon
  • C. B. Zamboni
  • M. F. Suzuki
  • C. R. BuenoJr.
  • T. O. Andrade
  • V. Landini
  • E. B. Cangussu
  • M. Zatz
Article
  • 92 Downloads

Abstract

Investigation in blood of specific elements concentration are an important step in the development of new treatments. Recently, studies with human adipose derived from stromal cells injected systemic (medication that affects the entire body) into a golden retriever muscular dystrophy dogs shown to be able to express improvements in skeletal muscle. To check the alterations that this cell therapy may cause in the dogs, elements concentration in blood of treated dogs were investigated using NAA. These results were compared with the control and affected (untreated) dogs groups showing an improvement in Ca and Fe blood levels in treated dogs.

Keywords

Blood NAA Inorganic elements Duchenne muscular dystrophy hASCs treatment Golden retriever 

Notes

Acknowledgments

We would like to acknowledge for financial support of the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Instituto de Pesquisas Energéticas e Nucleares (IPEN/CNEN-SP).

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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2015

Authors and Affiliations

  • S. Metairon
    • 1
  • C. B. Zamboni
    • 1
  • M. F. Suzuki
    • 1
  • C. R. BuenoJr.
    • 2
  • T. O. Andrade
    • 2
  • V. Landini
    • 2
  • E. B. Cangussu
    • 2
  • M. Zatz
    • 2
  1. 1.Instituto de Pesquisas Energéticas e Nucleares, IPEN – CNEN/SP, Centro do Reator de Pesquisa – CRPqSão PauloBrazil
  2. 2.Centro de Estudos do Genoma Humano, Instituto de BiociênciasSão PauloBrazil

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