Journal of Radioanalytical and Nuclear Chemistry

, Volume 262, Issue 3, pp 703–705 | Cite as

The absorption of iodine-131 on a ceramic matrix

  • H. S. Han
  • U. J. Park
  • A. Dash


The retention of 131I on ceramic rod coated with silver nitrate followed by coating with a polyurethane membrane to be applied in brachytherapy was studied. The concentration of silver nitrate (20 g/l), the volume of 131I as a sodium iodide solution (100 µl), the pH of the reaction mixture (pH 9) etc., were optimized to get a maximum uptake on the ceramic rod. The concentration of coating solution (5%, polyurethane in tetrahydrofuran) was also optimized to obtain a minimum leaching of 131I activity in normal saline solution. After coating with a polyurethane membrane, the 131I absorbed on the ceramic rod exhibited low leachability (0.03%). This method can be applied for the preparation of 125I interstitial sources to be used in eye and prostate cancer therapy.


Prostate Cancer Iodide Leaching Polyurethane Tetrahydrofuran 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    B. S. Cheng, S. Ali, Meigooni, R. Nath, Med. Dosim., 23 (1998) 259.Google Scholar
  2. 2.
    M. J. Rivard, Appl. Radiation Isotopes, 57 (2002) 381.Google Scholar
  3. 3.
    A. S. Meigooni, M. Darren, Gearheart, K. Sowards, Med. Phys., 27 (2000) 2168.Google Scholar
  4. 4.
    H. Hedtjarn, G. A. Carlsson, J. F. Williamson, Med. Phys., 27 (2000) 1076.Google Scholar
  5. 5.
    C. C. Popescu, J. Wise, K. Sowards, A. S. Meigooni, G. S. Ibbotm, Med. Phys., 27 (2000) 2174.Google Scholar
  6. 6.
    C. Mathew, M. A. Majali, S. A. Balakrishnan, Appl. Radiation Isotopes, 57 (2002) 359.Google Scholar
  7. 7.
    I. Puchalska, M. Mielcarski, Appl. Radiation Isotopes, 58 (2003) 15.Google Scholar
  8. 8.
    W. R. Lee, A. F. Deguzman, S. K. Tomlinson, D. L. McCullough, Radiother. Oncol., 65 (2002) 123.Google Scholar
  9. 9.
    K. Huang, P. K. Sneed, M. S. Berger, S. Kunwar, D. A. Larson, W. M. Wara, M. W. McDermott, Intern. J. Rad. Oncol. Biol. Phys., 54 (2002) 238.Google Scholar
  10. 10.
    N. E. Bechrakis, N. Bornfeld, I. Zöller, M. H. Foerster, Ophthalmology, 109 (2002) 1855.Google Scholar
  11. 11.
    T. Flam, S. Solignac, J. C. Rosenwald, N. Thiounn, F. Firmin, J. M. Cosset, L. Chauveinc, Cancer/Radiothérapie, 6 (2000) 154.Google Scholar
  12. 12.
    R. E. Wallace, Appl. Radiation Isotopes, 56 (2002) 581.Google Scholar
  13. 13.
    R. Nath, N. Yue, Appl. Radiation Isotopes, 55 (2001) 813.Google Scholar
  14. 14.
    L. Chauveinc, T. Flam, V. Servois, D. N’Guyen, J. C. Rosenwald, Cancer/Radiothérapie, 4 (2000) 253.Google Scholar
  15. 15.
    C. S. Wuu, R. D. Ennis, P. B. Schiff, E. K. Lee, M. Zaider, Intern. J. Radiat. Oncol. Biol. Phys., 47 (2000) 815.Google Scholar
  16. 16.
    H. Tabandeh, N. A. Chaudhry, T. G. Murray, F. Ehlies, R. Hughes, I. U. Scott, A. M. Markoe, Amer. J. Ophth., 129 (2000) 199.Google Scholar
  17. 17.
    W. Sauerwein, J. P. Gérard, Cancer/Radiothérapie, 3 (1999) 102.Google Scholar
  18. 18.
    B. V. Williams, J. Horton, A. Lawyer, J. Chapman, Med. Dosim., 24 (1999) 273.Google Scholar
  19. 19.
    R. Martínez-Monge, S. Nag, E. W. Martin, Intern. J. Radiat. Oncol. Biol. Phys., 42 (1998) 545.Google Scholar
  20. 20.
    J. Willins, K. Wallner, Intern. J. Radiat. Oncol. Biol. Phys., 39 (1999) 347.Google Scholar
  21. 21.
    F. M. Waterman, N. Yue, S. Reisinger, A. Dicker, B. W. Corn, Intern. J. Radiat. Oncol. Biol. Phys., 38 (1997) 335.Google Scholar
  22. 22.
    B. R. Prestidge, D. C. Hoak, P. D. Grimm, H. Ragde, W. Cavanagh, J. C. Blasko, Intern. J. Radiat. Oncol. Biol. Phys., 37 (1997) 31.Google Scholar
  23. 23.
    R. G. Stock, N. N. Stone, A. Tabert, J. K. Dewyngaert, Intern. J. Radiat. Oncol. Biol. Phys., 39 (1997) 221.Google Scholar
  24. 24.
    V. Feygelman, B. K. Noriega, R. M. Sanders, J. L. Friedland, Med. Dosim., 21 (1996) 261.Google Scholar

Copyright information

© Akadémiai Kiadó 2004

Authors and Affiliations

  1. 1.Korea Atomic Energy Research InstituteYusung, DaejeonKorea
  2. 2.Radiopharmaceuticals DivisionBhabha Atomic Research CentreTrombayIndia

Personalised recommendations